Multi-step polymer-assisted solution-phase (PASP) library synthesis of functionalized diaminobenzamides

• Published in: Combinatorial chemistry & high throughput screening Vol. 3; no. 2; p. 139
• Main Authors: South, M S, Case, B L, Dice, T A, Franklin, G W, Hayes, M J, Jones, D E, Lindmark, R J, Zeng, Q, Parlow, J J
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.04.2000
• Subjects: Amines - chemical synthesis; Benzamides - chemical synthesis; Chromatography, High Pressure Liquid; Combinatorial Chemistry Techniques - methods; Mass Spectrometry; Molecular Structure; Polymers - chemistry

A parallel solution-phase library synthesis of functionalized diaminobenzamides is described. The four-step library synthesis is accomplished using polymer-assisted solution-phase (PASP) synthesis techniques. This high-yielding, multi-step sequence utilizes sequestering resins for the removal of rea...