Clear cell sarcoma of tendons and aponeuroses: a review

• Published in: Archives of pathology & laboratory medicine (1976) Vol. 131; no. 1; pp. 152 - 156
• Main Authors: Dim, Daniel C, Cooley, Linda D, Miranda, Roberto N
• Format: Journal Article
• Language: English
• Published: United States College of American Pathologists 01.01.2007
• Subjects: Activating Transcription Factor 1; Analysis; Antigens; Antigens, Neoplasm; Calmodulin-Binding Proteins - genetics; Chromosomes; Cytoplasm; Diagnosis, Differential; Diseases; DNA-Binding Proteins - genetics; Ewings sarcoma; Humans; Medical prognosis; Melanoma; Melanoma-Specific Antigens; Metastasis; Neoplasm Proteins - metabolism; Neoplasms, Connective Tissue - diagnosis; Neoplasms, Connective Tissue - genetics; Neoplasms, Connective Tissue - metabolism; Neoplasms, Connective Tissue - pathology; Neoplasms, Connective Tissue - therapy; Nuclear Proteins - genetics; Polymerase chain reaction; Prognosis; Regulatory Factor X Transcription Factors; RNA-Binding Protein EWS; RNA-Binding Proteins - genetics; S100 Proteins - metabolism; Sarcoma; Sarcoma, Clear Cell - diagnosis; Sarcoma, Clear Cell - genetics; Sarcoma, Clear Cell - metabolism; Sarcoma, Clear Cell - pathology; Sarcoma, Clear Cell - therapy; Skin cancer; Tendons; Tendons - pathology; Transcription Factors; Translocation, Genetic; Tumors; Young adults

Clear cell sarcoma of tendons and aponeuroses, also referred to as malignant melanoma of soft parts, is a rare malignancy derived from neural crest cells. It usually presents in the distal lower extremities of young adults, frequently attached to tendons or aponeuroses. It behaves like a high-grade...