Significance of peripheral eosinophilia for diagnosis of IgG4-related disease in subjects with elevated serum IgG4 levels

• Published in: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] Vol. 20; no. 1; pp. 74 - 78
• Main Authors: Mohapatra, Sonmoon, Charilaou, Paris, Sharma, Ayush, Singh, Dhruv Pratap, Sah, Raghuwansh P., Murray, David, Majumder, Shounak, Topazian, Mark D., Chari, Suresh T.
• Format: Journal Article
• Language: English
• Published: Switzerland Elsevier B.V 01.01.2020; Elsevier Limited
• Subjects: Age; Asthma; Autoimmune pancreatitis; Binding sites; Blood diseases; Diagnosis; Electronic medical records; Eosinophilia; Gender; IgG4-related disease; IgG4-related pancreatobiliary disease; Immunoglobulin G; Laboratories; Lymphoma; Medical diagnosis; Patients; Peripheral eosinophilia; Serum IgG4 level; IgG4-related pancreatobiliary disease; IgG4-related disease; Peripheral eosinophilia; Autoimmune pancreatitis; Serum IgG4 level

In this study, we aim to assess the diagnostic utility of elevated serum IgG4 (sIgG4) concentration alone and in combination with peripheral eosinophilia (PE) for IgG4-related disease (IgG4-RD). From the Mayo Clinic, Rochester electronic medical record database we identified 409 patients with above...