Effects of Methotrexate on the Tubal Morphology of Rabbits: Evaluation by Electron Microscopy

• Published in: Gynecologic and obstetric investigation Vol. 65; no. 4; pp. 217 - 221
• Main Authors: Çetin, M. Turan, Arısoy, A. Hakim, Tap, Özgül, Kaya, Mehmet, Ürünsak, İbrahim
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland Karger 01.01.2008; S. Karger AG
• Subjects: Abortifacient Agents, Nonsteroidal - pharmacology; Animals; Biological and medical sciences; Epithelium - drug effects; Epithelium - ultrastructure; Fallopian Tubes - drug effects; Fallopian Tubes - pathology; Fallopian Tubes - ultrastructure; Female; Gynecology. Andrology. Obstetrics; Medical sciences; Methotrexate - pharmacology; Microscopy, Electron; Mitosis - drug effects; Original Article; Pregnancy; Rabbits; Electron microscopy; Methotrexate; Tubal morphology, rabbits; Antineoplastic agent; Gynecology; Rabbit; Lagomorpha; Fallopian tube; Obstetrics; Antifolate; Anatomic pathology; Vertebrata; Mammalia; Antimetabolic; Animal; Morphology

Background/Aims: To evaluate by electron microscopy the effects of methotrexate on the tubal morphology of rabbits. Methods: Biopsies were taken from the isthmic portion of both tubes of 4 rabbits in the control group. 1 mg/kg methotrexate was injected in the left tubes and as a control, a 14-gauge...