Dictyostelium discoideum to human cells: Pharmacogenetic studies demonstrate a role for sphingolipids in chemoresistance - Alexander, Stephen; Min, Junxia; Alexander, Hannah (Biochimica et biophysica acta, 2006)
Keywords: Aldehyde-Lyases - biosynthesis; Aldehyde-Lyases - genetics; Animals; Cancer therapy; Cell Line; Cell Line, Tumor; Ceramide; Cisplatin; Cisplatin - pharmacology; Dictyostelium - drug effects; Dictyostelium - genetics; Drug Resistance - genetics; Drug Resistance - physiology; Extracellular Signal-Regulated MAP Kinases - metabolism; Glutathione; Glutathione - metabolism; Humans; JNK Mitogen-Activated Protein Kinases - metabolism; MAP kinase; p38 Mitogen-Activated Protein Kinases - metabolism; Pharmacogenetics; Phosphotransferases (Alcohol Group Acceptor) - genetics; Signal transduction modulator; Sphingolipids - physiology; Sphingosine 1-phosphate; Cancer therapy; Signal transduction modulator; Ceramide; MAP kinase; Cisplatin; Sphingosine 1-phosphate; Glutathione