Effectiveness and Safety of Novel Nutraceutical Formulation Added to Ezetimibe in Statin-Intolerant Hypercholesterolemic Subjects with Moderate-to-High Cardiovascular Risk

• Published in: Journal of medicinal food Vol. 24; no. 1; p. 59
• Main Authors: Mazza, Alberto, Nicoletti, Mariaceleste, Lenti, Salvatore, Torin, Gioia, Rigatelli, Gianluca, Pellizzato, Marzia, Fratter, Andrea
• Format: Journal Article
• Language: English
• Published: United States 01.01.2021
• Subjects: Anticholesteremic Agents - therapeutic use; Cardiovascular Diseases - drug therapy; Dietary Supplements; Drug Therapy, Combination; Ezetimibe - therapeutic use; Heart Disease Risk Factors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects; Lipids - blood; Risk Factors; Treatment Outcome; bioavailability; ezetimibe; nutraceutical compounds; quercetin; cardiovascular risk; statin intolerance; LDL cholesterol; resveratrol; Monacolin-K

The effectiveness of statins in the primary and secondary prevention of cardiovascular (CV) diseases has been widely proven. However, the onset of adverse events associated with their use prevents to achieve the therapeutic targets recommended by the guidelines (GL) for the management of dyslipidemi...