Non-Ebola Filoviruses: Potential Threats to Global Health Security

• Published in: Viruses Vol. 16; no. 8; p. 1179
• Main Authors: Munyeku-Bazitama, Yannick, Edidi-Atani, Francois, Takada, Ayato
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 23.07.2024; MDPI
• Subjects: Animals; Bats; Disease Outbreaks; Disease transmission; Ebola virus; Ebolavirus; Ebolavirus - pathogenicity; Ebolavirus - physiology; Epidemics; Fatalities; Fever; Filoviridae; Filoviridae - pathogenicity; Filoviridae Infections - epidemiology; Filoviridae Infections - virology; Filovirus; Genomes; Global Health; Hemorrhagic fever; Hemorrhagic Fever, Ebola - epidemiology; Hemorrhagic Fever, Ebola - transmission; Hemorrhagic Fever, Ebola - virology; Host range; Humans; Infectious diseases; Marburg disease; Marburg virus; non-Ebola filovirus; Pathogenicity; Pest outbreaks; Public health; Ravn virus; Reston virus; Review; RNA polymerase; RNA viruses; Sudan virus; Vaccines; Viruses; Zoonoses - epidemiology; Zoonoses - virology; Mozambique; South Sudan; United States > US; Philippines; China; Sudan; Italy; Uganda; Sierra Leone; Congo-Democratic Republic of Congo; Kenya; Spain; Sudan virus; Ravn virus; Marburg virus; Mengla virus; Dehong virus; Bundibugyo virus; Bombali virus; Filovirus; Lloviu virus; non-Ebola filovirus; Reston virus; Taï Forest virus

Filoviruses are negative-sense single-stranded RNA viruses often associated with severe and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality rates as high as 90%. Of the known filoviruses, Ebola virus (EBOV), the prototype of the genus , has been a major public hea...