Safety profile of meropenem: international clinical experience based on the first 3125 patients treated with meropenem

• Published in: Journal of antimicrobial chemotherapy Vol. 36 Suppl A; p. 207
• Main Authors: Norrby, S R, Newell, P A, Faulkner, K L, Lesky, W
• Format: Journal Article
• Language: English
• Published: England 01.07.1995
• Subjects: Bacterial Infections - drug therapy; Bacterial Infections - microbiology; Carbapenems - administration & dosage; Carbapenems - adverse effects; Child; Clinical Trials, Phase III as Topic; Humans; Meropenem; Prospective Studies; Randomized Controlled Trials as Topic; Thienamycins - administration & dosage; Thienamycins - adverse effects; Treatment Outcome

Data from 3125 patients (3220 patient exposures) treated with meropenem were compared with those from 2886 patients (2960 patient exposures) treated with a variety of comparator agents including cephalosporins (alone or in combination with aminoglycosides or an anti-anaerobe agent) and imipenem/cila...