Availability of specific sugars for glycoconjugate biosynthesis: A need for further investigations in man

• Published in: Biochimie Vol. 80; no. 1; pp. 75 - 86
• Main Authors: Martin, A., Rambal, C., Berger, V., Perier, S., Louisot, P.
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 1998
• Subjects: Animals; Carbohydrate Metabolism; dietary sugars; Glycoconjugates - biosynthesis; glycoprotein biosynthesis; Glycoproteins - metabolism; Glycosylation; Humans; Isotopes; Nutritional Physiological Phenomena; stable isotopes; glycoprotein biosynthesis; dietary sugars; stable isotopes

We review the metabolism of specific sugars used for protein glycosylation, focusing on the fate of exogenously provided sugars. Theoretically, all glycoprotein sugars can derive from glucose, but previous studies show that other exogenous sugars can be incorporated into glycoproteins. From data obt...