Common pathways for primary hypertrophic and dilated cardiomyopathy

• Published in: Hybridoma and hybridomics Vol. 22; no. 1; p. 41
• Main Authors: Kroumpouzou, E, Gomatos, I P, Kataki, A, Karayannis, M, Dangas, G D, Toutouzas, P
• Format: Journal Article
• Language: English
• Published: United States 01.02.2003
• Subjects: Cardiomyopathy, Dilated - etiology; Cardiomyopathy, Hypertrophic - etiology; Humans; Oncogenes - physiology; Proto-Oncogene Proteins c-fos - genetics; Proto-Oncogene Proteins c-fos - metabolism; Proto-Oncogene Proteins c-myc - genetics; Proto-Oncogene Proteins c-myc - metabolism; ras Proteins - genetics; ras Proteins - metabolism

Testing the hypothesis that hypertrophic and dilated cardiomyopathy as well as viral myocarditis share a common mitogenic growth response pathway with mitotically competent cell types are the aims of this study. The expression of the c-fos, H-ras and c-myc genes was immunohistochemically determined...