Comparison of cefotetan and cefoxitin prophylaxis for abdominal and vaginal hysterectomy

• Published in: American journal of obstetrics and gynecology Vol. 158; no. 3 Pt 2; p. 706
• Main Authors: Berkeley, A S, Freedman, K S, Ledger, W J, Orr, J W, Benigno, B B, Gordon, S F, McGregor, J A, Galask, R P, Sevin, B U
• Format: Journal Article
• Language: English
• Published: United States 01.03.1988
• Subjects: Abdomen; Adult; Cefotetan; Cefoxitin - administration & dosage; Cefoxitin - therapeutic use; Cephamycins - administration & dosage; Cephamycins - therapeutic use; Female; Genital Diseases, Female - prevention & control; Humans; Hysterectomy; Hysterectomy, Vaginal; Infection Control; Middle Aged; Postoperative Complications - prevention & control; Prospective Studies; Random Allocation; Surgical Wound Infection - prevention & control

The safety and efficacy of parenteral prophylaxis with either cefotetan or cefoxitin were evaluated in a prospective, randomized study of 355 subjects undergoing abdominal or vaginal hysterectomy. Each subject received either a single 1 gm dose of cefotetan intravenously 30 to 60 minutes before oper...