Investigation of Genetic Variants Associated with Alzheimer Disease in Parkinson Disease Cognition

• Published in: Journal of Parkinson's disease Vol. 6; no. 1; pp. 119 - 124
• Main Authors: Barrett, Matthew J., Koeppel, Alexander F., Flanigan, Joseph L., Turner, Stephen D., Worrall, Bradford B.
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.01.2016
• Subjects: Aged; Alzheimer Disease - etiology; Alzheimer Disease - genetics; Cognition; Female; Genetic Predisposition to Disease - genetics; Genome-Wide Association Study; Genotype; Humans; Male; Middle Aged; Monomeric Clathrin Assembly Proteins - genetics; Parkinson Disease - complications; Parkinson Disease - genetics; Polymorphism, Single Nucleotide - genetics; Parkinson disease; dementia; mild cognitive impairment; genetics; Alzheimer disease

Background: Meta-analysis of genome-wide association studies have implicated multiple single nucleotide polymorphisms (SNPs) and associated genes with Alzheimer disease. The role of these SNPs in cognitive impairment in Parkinson disease (PD) remains incompletely evaluated. Objective: The objective...