Detection and quantitation of normal and variant haemoglobins: an analytical review

• Published in: Annals of Clinical Biochemistry Vol. 41; no. 5; pp. 355 - 369
• Main Authors: Wild, Barbara J, Bain, Barbara J
• Format: Book Review Journal Article
• Language: English
• Published: London, England SAGE Publications 01.09.2004; Sage Publications Ltd
• Subjects: Animals; Genetic Variation; Hemoglobins - analysis; Hemoglobins - genetics; Hemoglobins, Abnormal - analysis; Hemoglobins, Abnormal - genetics; Humans

As well as six 'normal' haemoglobins that occur at various stages of development, more than 800 abnormal or variant haemoglobins have been described. Many of these variant haemoglobins have no significant clinical consequences apart from causing confusion to clinicians and in laboratories;...