Temporal Trends in the Association Between Female Sex and Ischemic Stroke Among Patients With Atrial Fibrillation

• Published in: Journal of the American Heart Association Vol. 14; no. 13; p. e040325
• Main Authors: Mills, Mark T., Bucci, Tommaso, Calvert, Peter, Gupta, Dhiraj, Lip, Gregory Y. H.
• Format: Journal Article
• Language: English
• Published: England Wiley 01.07.2025
• Subjects: Aged; Aged, 80 and over; atrial fibrillation; Atrial Fibrillation - complications; Atrial Fibrillation - diagnosis; Atrial Fibrillation - epidemiology; Cause of Death - trends; Female; female sex; Humans; Incidence; Ischemic Stroke - diagnosis; Ischemic Stroke - epidemiology; Ischemic Stroke - etiology; Male; Middle Aged; Retrospective Studies; Risk Assessment; Risk Factors; risk prediction; Sex Factors; stroke; temporal trends; Time Factors; female sex; atrial fibrillation; stroke; temporal trends; risk prediction

Female sex has historically been associated with higher risk of ischemic stroke in patients with atrial fibrillation. However, contemporary European studies suggest this association may have attenuated and become nonsignificant over recent years. This study aims to characterize temporal trends in ca...