Human Pulmonary Infection by the Zoonotic Metastrongylus salmi Nematode. The First Reported Case in the Americas

Pulmonary metastrongylosis, a zoonotic disease found primarily in pigs, is caused by eight different species of the cosmopolitan nematode Metastrongylus genus. To date, only four human cases have been reported, all from Europe. Herein, a severe case of pulmonary infection caused by Metastrongylus sa...

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Published inThe American Society of Tropical Medicine and Hygiene Vol. 95; no. 4; pp. 871 - 873
Main Authors Calvopina, Manuel, Caballero, Henry, Morita, Tatsushi, Korenaga, Masataka
Format Journal Article
LanguageEnglish
Published United States American Society of Tropical Medicine and Hygiene 05.10.2016
The American Society of Tropical Medicine and Hygiene
SeriesCase Report
Subjects
Animals
Antiparasitic Agents
Antiparasitic Agents - therapeutic use
Ecuador
Humans
Ivermectin
Ivermectin - therapeutic use
Male
Metastrongyloidea
Metastrongyloidea - isolation & purification
Metastrongyloidea - ultrastructure
Middle Aged
Nematoda
Pneumonia
Pneumonia - diagnosis
Pneumonia - drug therapy
Sputum
Sputum - parasitology
Strongylida Infections
Strongylida Infections - diagnosis
Strongylida Infections - drug therapy
ANE, Europe
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Abstract Pulmonary metastrongylosis, a zoonotic disease found primarily in pigs, is caused by eight different species of the cosmopolitan nematode Metastrongylus genus. To date, only four human cases have been reported, all from Europe. Herein, a severe case of pulmonary infection caused by Metastrongylus salmi in an Ecuadorian man, with successful treatment with ivermectin, is described.
AbstractList Pulmonary metastrongylosis, a zoonotic disease found primarily in pigs, is caused by eight different species of the cosmopolitan nematode Metastrongylus genus. To date, only four human cases have been reported, all from Europe. Herein, a severe case of pulmonary infection caused by Metastrongylus salmi in an Ecuadorian man, with successful treatment with ivermectin, is described.
Pulmonary metastrongylosis, a zoonotic disease found primarily in pigs, is caused by eight different species of the cosmopolitan nematode Metastrongylus genus. To date, only four human cases have been reported, all from Europe. Herein, a severe case of pulmonary infection caused by Metastrongylus salmi in an Ecuadorian man, with successful treatment with ivermectin, is described.
Author Henry Caballero
Manuel Calvopiña
Masataka Korenaga
Tatsushi Morita
AuthorAffiliation 3 Laboratory of Veterinary Parasitology, Nippon Veterinary and Life Science University, Musashino, Japan
4 Department of Parasitology, Kochi Medical School, Kochi University, Kochi, Japan
1 Centro de Biomedicina, Carrera de Medicina, Universidad Central del Ecuador, Quito, Ecuador
2 Servicio de Terapia Intensiva, Hospital Oncológico Sociedad de Lucha Contra el Cáncer (SOLCA), Quito, Ecuador
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References Chatin (ref13) 1888; 52
Beaver (ref1) 1984
(ref11) 2009–2015
Márquez (ref10) 2008
Solaymani-Mohammadi (ref14) 2003; 77
Amunárriz (ref4) 1984
Teuscher (ref8) 1968; 16
Miloshev (ref5) 1956; 7
Noda (ref7) 1973; 25
Morita (ref2) 2007; 69
Monar (ref9) 2005
Gassó (ref6) 2014; 119
Rainey (ref12) 1855; 6
Forrester (ref3) 1982; 181
12895286 - J Helminthol. 2003 Sep;77(3):263-7
13433513 - Suvr Med (Sofiia). 1956;7(11):94-7
7174442 - J Am Vet Med Assoc. 1982 Dec 1;181(11):1278-80
25060317 - Parasitol Res. 2014 Sep;113(9):3495-500
17485932 - J Vet Med Sci. 2007 Apr;69(4):417-20
References_xml – start-page: 291
  year: 1984
  ident: ref1
– start-page: 1
  year: 2008
  ident: ref10
– start-page: 45
  year: 1984
  ident: ref4
– volume: 77
  start-page: 263
  year: 2003
  ident: ref14
  article-title: Helminth parasites of the wild boar, Sus scrofa, in Luristan province, western Iran and their public health significance
– start-page: 1
  year: 2005
  ident: ref9
– volume: 16
  start-page: 60
  year: 1968
  ident: ref8
  article-title: Tetramisol en cerdos: ensayos efectuados en el Ecuador con animales naturalmente infestados por Metastrongylus y otros nematodos
– volume: 25
  start-page: 21
  year: 1973
  ident: ref7
  article-title: A new species of Metastrongylus (Nematoda) from a wild boar with remarks on other species
– volume: 6
  start-page: 370
  year: 1855
  ident: ref12
  article-title: Entozoon found in the larynx
– volume: 119
  start-page: 3495
  year: 2014
  ident: ref6
  article-title: An identification key for the five most common species of Metastrongylus
– volume: 52
  start-page: 482
  year: 1888
  ident: ref13
  article-title: Strongle Paradoxal Chez L'homme
– volume: 69
  start-page: 417
  year: 2007
  ident: ref2
  article-title: Lung worms of wild boars in the western region of Tokyo, Japan
– year: 2009–2015
  ident: ref11
– volume: 7
  start-page: 94
  year: 1956
  ident: ref5
  article-title: Case of triple infection with Metastrongylus elongatus, Thaeniarhynchus saginatus and Enterobius vermicularis [in Bulgarian]
– volume: 181
  start-page: 1278
  year: 1982
  ident: ref3
  article-title: Lungworms of feral swine in Florida
– reference: 13433513 - Suvr Med (Sofiia). 1956;7(11):94-7
– reference: 7174442 - J Am Vet Med Assoc. 1982 Dec 1;181(11):1278-80
– reference: 25060317 - Parasitol Res. 2014 Sep;113(9):3495-500
– reference: 17485932 - J Vet Med Sci. 2007 Apr;69(4):417-20
– reference: 12895286 - J Helminthol. 2003 Sep;77(3):263-7
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Snippet Pulmonary metastrongylosis, a zoonotic disease found primarily in pigs, is caused by eight different species of the cosmopolitan nematode Metastrongylus genus....
Pulmonary metastrongylosis, a zoonotic disease found primarily in pigs, is caused by eight different species of the cosmopolitan nematode Metastrongylus genus....
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SubjectTerms Animals
Antiparasitic Agents
Antiparasitic Agents - therapeutic use
Ecuador
Humans
Ivermectin
Ivermectin - therapeutic use
Male
Metastrongyloidea
Metastrongyloidea - isolation & purification
Metastrongyloidea - ultrastructure
Middle Aged
Nematoda
Pneumonia
Pneumonia - diagnosis
Pneumonia - drug therapy
Sputum
Sputum - parasitology
Strongylida Infections
Strongylida Infections - diagnosis
Strongylida Infections - drug therapy
Title Human Pulmonary Infection by the Zoonotic Metastrongylus salmi Nematode. The First Reported Case in the Americas
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