Topical glutathione amino acid precursors protect skin against environmental and oxidative stress

• Published in: Journal of the European Academy of Dermatology and Venereology Vol. 38; no. S3; pp. 3 - 11
• Main Authors: Cui, Xiao, Mi, Tingyan, Xiao, Xue, Zhang, Hong, Dong, Yiying, Huang, Nan, Gao, Ping, Lee, Jianming, Guelakis, Marian, Gu, Xuelan
• Format: Journal Article
• Language: English
• Published: England 01.01.2024
• Subjects: Adenosine Triphosphate; Amino Acids; Ascorbic Acid - pharmacology; Chromatography, Liquid; Female; Glutathione; Glutathione Disulfide; Humans; Oxidative Stress; Reactive Oxygen Species; Tandem Mass Spectrometry; Vitamin K 3

Background Although glutathione (GSH) has long been considered a master antioxidant, poor stability and bioavailability limit its application in skin protection. To overcome the challenges, Unilever R&D formulated a Glutathione Amino acid Precursors blend (named GAP) to boost GSH de novo synthes...