Changes in knee adduction moment wearing a variable‐stiffness shoe correlate with changes in pain and mechanically stimulated cartilage oligomeric matrix levels

• Published in: Journal of orthopaedic research Vol. 39; no. 3; pp. 619 - 627
• Main Authors: Erhart‐Hledik, Jennifer C., Mahtani, Gordhan B., Asay, Jessica L., Migliore, Eleonora, Nguyen, Michelle M., Andriacchi, Thomas P., Chu, Constance R.
• Format: Journal Article
• Language: English
• Published: United States 01.03.2021
• Subjects: Aged; cartilage oligomeric matrix protein; Cartilage Oligomeric Matrix Protein - blood; Female; Foot Orthoses - statistics & numerical data; Humans; knee adduction moment; Knee Joint - physiology; Male; Middle Aged; osteoarthritis; Osteoarthritis, Knee - blood; Osteoarthritis, Knee - complications; Osteoarthritis, Knee - therapy; pain; Pain - etiology; Pain - prevention & control; Prospective Studies; Severity of Illness Index; Shoes - statistics & numerical data; variable‐stiffness shoe; Weight-Bearing; knee adduction moment; pain; variable-stiffness shoe; cartilage oligomeric matrix protein; osteoarthritis

This study aimed to determine if changes in knee adduction moment (KAM) after 6 months of variable‐stiffness shoe wear are associated with changes in symptoms or serum levels of cartilage oligomeric matrix protein (COMP) following a mechanical stimulus in subjects with medial knee osteoarthritis (OA...