Effects of intranasal oxytocin on pain perception among human subjects: A systematic literature review and meta-analysis

• Published in: Hormones and behavior Vol. 147; p. 105282
• Main Authors: Lopes, Samuel, Osório, Flávia de Lima
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2023
• Subjects: Administration, Intranasal; Analgesia; Human subjects; Humans; Nociception; Oxytocin; Oxytocin - pharmacology; Oxytocin - therapeutic use; Pain - drug therapy; Pain perception; Pain Perception - drug effects; Nociception; Human subjects; Analgesia; Pain perception; Oxytocin

Oxytocin (OXT) is a peptide hormone produced in the hypothalamus that plays a neuromodulatory role in emotion, stress, and anxiety. Due to its multidimensional role, OXT is a promising target for therapeutic interventions to treat pain. Perform a systematic literature review, followed by a meta-anal...