The pharmacology of the cytochrome P450 epoxygenase/soluble epoxide hydrolase axis in the vasculature and cardiovascular disease

Over the last 20 years, it has become clear that cytochrome P450 (P450) enzymes generate a spectrum of bioactive lipid mediators from endogenous substrates. However, studies focused on the determining biologic activity of the P450 system have focused largely on the metabolites generated by one subst...

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Bibliographic Details
Published inPharmacological reviews Vol. 66; no. 4; pp. 1106 - 1140
Main Author Fleming, Ingrid
Format Journal Article
LanguageEnglish
Published United States 01.10.2014
Subjects
Animals
Arachidonic Acid - metabolism
Cardiovascular Diseases - physiopathology
Cytochrome P-450 Enzyme System - metabolism
Epoxide Hydrolases - metabolism
Humans
Inflammation - metabolism
Neovascularization, Physiologic - physiology
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Abstract Over the last 20 years, it has become clear that cytochrome P450 (P450) enzymes generate a spectrum of bioactive lipid mediators from endogenous substrates. However, studies focused on the determining biologic activity of the P450 system have focused largely on the metabolites generated by one substrate (i.e., arachidonic acid). However, epoxides and diols derived from other endogenous substrates, such as linoleic acid, eicosapentaenoic acid, and docosahexaenoic acid, may be generated in higher concentrations and may potentially be of more physiologic relevance. Recent studies that used a combination of phenotyping and lipid array analyses revealed that rather than being inactive products, fatty acid diols play important roles in a number of biologic processes including inflammation, angiogenesis, and metabolic regulation. Moreover, inhibitors of the soluble epoxide hydrolase that increase epoxide but decrease diol levels have potential for the treatment of the metabolic syndrome.
AbstractList Over the last 20 years, it has become clear that cytochrome P450 (P450) enzymes generate a spectrum of bioactive lipid mediators from endogenous substrates. However, studies focused on the determining biologic activity of the P450 system have focused largely on the metabolites generated by one substrate (i.e., arachidonic acid). However, epoxides and diols derived from other endogenous substrates, such as linoleic acid, eicosapentaenoic acid, and docosahexaenoic acid, may be generated in higher concentrations and may potentially be of more physiologic relevance. Recent studies that used a combination of phenotyping and lipid array analyses revealed that rather than being inactive products, fatty acid diols play important roles in a number of biologic processes including inflammation, angiogenesis, and metabolic regulation. Moreover, inhibitors of the soluble epoxide hydrolase that increase epoxide but decrease diol levels have potential for the treatment of the metabolic syndrome.
Author Fleming, Ingrid
Author_xml – sequence: 1
  givenname: Ingrid
  surname: Fleming
  fullname: Fleming, Ingrid
  email: fleming@em.uni-frankfurt.de
  organization: Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany fleming@em.uni-frankfurt.de
BackLink https://www.ncbi.nlm.nih.gov/pubmed/25244930$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1089/ars.2013.5466
10.1152/physrev.00021.2011
10.1152/ajpendo.00131.2009
10.3390/ijms141123086
10.1042/CS20130479
10.1016/j.cell.2009.01.015
10.1073/pnas.1304321110
10.1006/abio.1998.2897
10.1016/j.prostaglandins.2011.07.005
10.1074/jbc.M709873200
10.1016/0166-2236(96)10040-0
10.1021/jm200132q
10.1371/journal.pone.0083310
10.1016/j.yjmcc.2013.02.003
10.1016/S0140-6736(03)13081-4
10.1016/0014-2999(95)00861-6
10.1016/j.jtcvs.2013.03.015
10.1242/jcs.02674
10.1172/JCI58128
10.1089/ars.2013.5473
10.1152/ajpheart.00427.2005
10.1016/j.ceca.2009.02.007
10.1002/(SICI)1096-9888(199708)32:8<888::AID-JMS548>3.0.CO;2-W
10.1371/journal.pone.0026591
10.1097/MNH.0b013e32835d911e
10.1007/BF02522457
10.1016/j.pharmthera.2009.12.002
10.1124/jpet.110.167544
10.1016/j.cell.2010.07.041
10.1074/jbc.M110.118406
10.1158/1541-7786.MCR-05-0101
10.1016/j.bbrc.2011.06.132
10.1161/CIRCULATIONAHA.110.990317
10.1152/ajpheart.00318.2005
10.1152/ajpheart.01079.2005
10.1016/j.tips.2008.05.003
10.1016/S0002-9440(10)63142-2
10.1371/journal.pone.0039197
10.1016/j.gene.2013.05.008
10.1124/mol.60.2.310
10.1074/jbc.M501730200
10.1124/jpet.108.145102
10.1007/s10038-003-0103-6
10.1523/JNEUROSCI.5793-11.2012
10.1161/ATVBAHA.107.161190
10.1124/jpet.111.179036
10.1111/j.1365-2710.2009.01146.x
10.1111/j.1476-5381.2011.01641.x
10.1016/j.jnutbio.2014.02.004
10.1097/MCO.0b013e32835c5f29
10.1038/ki.2013.187
10.1152/ajpheart.00001.2013
10.1074/jbc.M110806200
10.1111/j.1528-1157.1995.tb01645.x
10.1093/hmg/ddi315
10.1371/journal.pone.0011979
10.1074/jbc.M110299200
10.1016/j.bbagrm.2010.09.006
10.1016/j.cccn.2004.04.028
10.1016/S0009-8981(00)00264-3
10.1016/S0021-9258(20)89484-8
10.1016/j.prostaglandins.2010.12.001
10.1016/j.addr.2011.03.006
10.1161/01.STR.0000037787.07479.9A
10.1161/01.HYP.0000208299.62535.58
10.1097/FJC.0b013e31827afcee
10.1021/bi050842g
10.1016/S0090-6980(03)00002-9
10.1002/jps.22639
10.1096/fasebj.6.2.1537454
10.1016/S0891-5849(97)00463-2
10.1111/joim.12016
10.1080/10739680500466400
10.1152/ajprenal.00350.2004
10.1016/j.cell.2011.08.039
10.1124/jpet.105.083477
10.1210/jc.2009-1669
10.1016/j.yjmcc.2009.01.009
10.1161/ATVBAHA.110.204099
10.1073/pnas.0508081102
10.1016/j.cmet.2012.04.009
10.1164/rccm.200806-848OC
10.1021/cr100396c
10.1002/med.10050
10.1210/en.2012-2012
10.1016/j.pharmthera.2013.10.010
10.1096/fj.11-0502ufm
10.1074/jbc.M112.407981
10.1074/jbc.M113.481077
10.1097/MCO.0b013e3283479230
10.1016/j.bbrc.2005.12.180
10.1016/j.immuni.2006.10.015
10.1006/bbrc.1993.1803
10.1016/j.lfs.2006.07.031
10.1096/fj.12-218040
10.1042/BJ20021903
10.1111/j.1349-7006.2010.01713.x
10.1074/jbc.M109.054759
10.1073/pnas.1103482108
10.1074/jbc.271.24.14001
10.1016/j.ejphar.2012.12.015
10.1194/jlr.M017319
10.1021/pr4004739
10.1097/FJC.0b013e318185fa3c
10.1073/pnas.0409591102
10.1681/ASN.2009111110
10.1038/jcbfm.2013.130
10.1021/jm301617j
10.1152/ajpheart.00125.2002
10.1073/pnas.1101073108
10.1196/annals.1375.019
10.1152/ajpheart.00831.2001
10.1007/978-94-007-0265-3_42
10.1387/ijdb.103067cc
10.1016/j.toxlet.2014.02.026
10.1124/jpet.105.091876
10.1152/ajpcell.00230.2008
10.1161/HYPERTENSIONAHA.109.146399
10.1016/B978-0-12-385061-4.00002-7
10.1007/s10735-006-9050-9
10.1124/jpet.110.174805
10.1016/j.prostaglandins.2011.06.009
10.1097/CCM.0000000000000226
10.1016/j.atherosclerosis.2013.01.034
10.1124/mol.62.5.1076
10.1085/jgp.200409140
10.1016/S0022-2275(20)32049-6
10.1016/j.plefa.2013.12.008
10.1161/01.HYP.0000246672.72188.bd
10.1016/j.yjmcc.2008.09.711
10.1124/dmd.106.013839
10.1113/expphysiol.2007.038612
10.1126/science.285.5431.1276
10.1161/hy0202.103420
10.1152/ajpheart.00844.2002
10.1124/mol.113.087122
10.1016/S0090-6980(00)00079-4
10.1097/00003246-199602000-00010
10.1002/path.2611
10.1093/cvr/cvr267
10.1038/sj.bjp.0706256
10.1016/j.bcp.2011.07.100
10.1016/j.yjmcc.2009.02.028
10.1177/1076029610364522
10.1161/01.RES.0000187474.47805.30
10.1161/ATVBAHA.109.186064
10.1016/j.prostaglandins.2013.01.002
10.1016/j.bbamem.2008.10.011
10.1021/jm301194c
10.1038/sj.bjp.0702078
10.1016/S1097-2765(00)80342-1
10.1258/ebm.2012.012225
10.1111/j.1549-8719.2012.00202.x
10.1016/j.taap.2004.12.022
10.1124/jpet.108.136739
10.1371/journal.pone.0076575
10.1161/01.STR.0000016332.37292.59
10.1007/s00395-012-0319-8
10.1017/S0029665110000157
10.1155/2012/758614
10.1161/01.RES.78.3.415
10.1007/s00424-010-0830-4
10.1161/CIRCRESAHA.111.259325
10.1073/pnas.92.3.905
10.1371/journal.pone.0069913
10.1100/tsw.2010.99
10.1016/j.bbagrm.2007.11.005
10.1016/j.bbapap.2010.09.009
10.1161/01.CIR.94.12.3341
10.4049/jimmunol.1300699
10.1073/pnas.0809765105
10.1124/mol.106.023648
10.1210/en.2012-2166
10.1152/ajpheart.01122.2011
10.1016/j.molmed.2012.02.002
10.1016/j.pharmthera.2005.11.003
10.1074/jbc.M110.182329
10.1124/jpet.109.157818
10.1016/0006-2952(94)90235-6
10.1016/j.bbrc.2012.02.108
10.1038/nature01807
10.1124/jpet.105.085605
10.1097/00008571-200401000-00001
10.1016/S0163-7827(02)00002-4
10.1124/jpet.303.2.768
10.1194/jlr.M022319
10.1152/ajpregu.00606.2011
10.1161/hy1201.096532
10.1038/nature02196
10.1038/cddis.2013.418
10.1371/journal.pone.0046065
10.1124/dmd.106.012823
10.1016/j.jjcc.2009.06.004
10.2337/db09-1241
10.1093/cvr/cvn207
10.1074/jbc.M110.198515
10.1038/nm0597-562
10.1161/HYPERTENSIONAHA.113.01949
10.2174/1874073100701010001
10.1007/s004280050359
10.1046/j.1471-4159.1995.65010338.x
10.1073/pnas.0308185100
10.1002/jcb.22709
10.1093/cvr/cvt095
10.1096/fj.02-0640fje
10.1124/jpet.111.180505
10.1517/13543776.2014.899583
10.1111/j.1469-7793.1997.099bi.x
10.1093/carcin/bgu001
10.1021/cr200131e
10.1074/jbc.M113.458414
10.1073/pnas.1011278107
10.1002/mc.20589
10.1161/ATVBAHA.107.152074
10.1021/bi102070w
10.1167/iovs.11-6729
10.1152/ajpheart.01118.2001
10.1113/jphysiol.1996.sp021801
10.1093/jn/129.1.70
10.1152/ajpheart.00983.2008
10.1124/mol.59.1.16
10.1016/S0165-6147(02)02050-3
10.1158/0008-5472.CAN-06-1403
10.1016/j.taap.2011.12.009
10.1016/j.prostaglandins.2012.08.001
10.1161/JAHA.113.000080
10.1042/CS20130003
10.1016/0167-4781(91)90138-C
10.1007/112_2011_2
10.1016/j.ahj.2010.10.021
10.1161/01.HYP.36.2.270
10.1073/pnas.0703229104
10.1016/j.yjmcc.2012.04.008
10.1074/jbc.M806315200
10.1161/hy0202.103293
10.1152/ajprenal.00038.2008
10.1074/jbc.M113.508416
10.1161/HYPERTENSIONAHA.114.03275
10.1074/jbc.M608057200
10.1006/bbrc.1999.1313
10.1111/j.1476-5381.1996.tb15327.x
10.1111/j.1478-3231.2011.02509.x
10.1084/jem.20131494
10.1016/j.bbalip.2013.10.006
10.1038/nrd2875
10.1074/jbc.M113.525659
10.1073/pnas.0437724100
10.1161/CIRCRESAHA.110.235879
10.1021/jm2001376
10.1161/01.RES.80.6.877
10.1007/s12263-014-0405-7
10.1016/j.plefa.2012.06.001
10.1046/j.1440-1681.2003.03921.x
10.1007/s00424-013-1356-3
10.1113/jphysiol.2002.030833
10.1016/j.resuscitation.2007.06.031
10.1007/s00424-013-1411-0
10.1006/abbi.1999.1138
10.1055/s-0029-1243604
10.1124/jpet.109.157545
10.1038/ng.389
10.1161/01.CIR.0000105763.51286.7F
10.1007/978-1-60761-500-2_12
10.1016/j.bbrc.2005.02.103
10.3109/08037051.2010.542640
10.1111/j.1440-1681.2011.05492.x
10.1016/0006-2952(89)90528-5
10.1161/01.RES.0000139436.89654.c8
10.1016/S0021-9258(19)49601-4
10.1371/journal.pone.0007421
10.1139/y2012-082
10.1016/j.prostaglandins.2011.09.001
10.1097/MCO.0b013e3283439622
10.1016/j.nutres.2013.07.004
10.1007/s00441-012-1485-6
10.1093/cvr/cvp281
10.1097/00005344-199810000-00018
10.1016/j.prostaglandins.2006.05.017
10.1016/j.bpj.2012.06.016
10.1152/ajpcell.00139.2013
10.1074/jbc.M701429200
10.1124/dmd.112.046466
10.1152/ajprenal.00098.2009
10.1016/S0021-9258(18)91081-1
10.1074/jbc.M201575200
10.1097/FJC.0b013e3181e96e0c
10.1016/j.atherosclerosis.2012.03.022
10.1111/j.1469-7793.1998.561bq.x
10.1182/blood-2009-09-243139
10.1074/jbc.M100439200
10.1523/JNEUROSCI.15-07-04738.1995
10.1007/s11745-013-3774-6
10.1152/ajpheart.00423.2004
10.1016/j.biochi.2013.11.006
10.1073/pnas.0811022106
10.3109/08977199709021522
10.1016/j.abb.2009.05.006
10.1016/S0008-6363(02)00257-2
10.1007/s00424-010-0804-6
10.1152/ajpendo.00370.2011
10.1158/0008-5472.CAN-06-3643
10.1124/jpet.113.210120
10.1161/ATVBAHA.113.302927
10.1161/JAHA.112.005033
10.1152/ajpcell.00153.2009
10.1038/24388
10.1038/onc.2013.264
10.1002/cmdc.201100433
10.1113/jphysiol.2006.113985
10.1152/ajplung.90436.2008
10.1016/j.clnu.2010.07.011
10.1146/annurev-nutr-010411-095239
10.1152/ajpheart.00516.2005
10.1097/FJC.0b013e318298e460
10.1124/jpet.107.129577
10.1096/fj.11-188300
10.1254/jphs.12079FP
10.1002/cphy.c110051
10.1096/fj.08-112821
10.1161/01.RES.87.11.992
10.1152/ajpregu.00018.2004
10.1016/S0163-7827(03)00038-9
10.1124/mol.61.2.255
10.1152/ajpheart.2000.279.4.H1526
10.1038/sj.bjp.0703188
10.1097/FJC.0b013e3181506445
10.1016/j.lfs.2008.06.026
10.1016/j.atherosclerosis.2006.02.021
10.1152/ajprenal.00597.2010
10.1016/j.bbrc.2007.01.028
10.1074/jbc.M107228200
10.1007/s13105-013-0303-2
10.1172/JCI27546
10.1152/ajpcell.1999.277.5.C870
10.1161/01.RES.84.1.53
10.1007/978-1-4899-1813-0_85
10.1007/s12038-007-0028-x
10.1152/ajpheart.01052.2002
10.1016/j.abb.2008.01.002
10.1007/s11883-013-0389-6
10.1152/ajplung.2000.278.2.L335
10.1021/jm900634w
10.1016/j.taap.2004.12.027
10.1006/dbio.2000.9957
10.1161/HYPERTENSIONAHA.110.151423
10.1007/s13318-011-0024-2
10.1016/j.vph.2009.08.003
10.1161/01.ATV.19.3.680
10.1016/j.ejheart.2007.05.005
10.1515/hsz-2013-0251
10.1016/j.bcp.2009.10.025
10.1038/oby.2009.227
10.1161/HYPERTENSIONAHA.111.178475
10.1124/jpet.114.214254
10.1124/mol.104.004150
10.1007/s00232-008-9145-1
10.1161/01.HYP.0000153792.29478.1d
10.1016/j.chemphyslip.2008.02.010
10.1161/01.RES.88.1.44
10.1073/pnas.092671899
10.1161/01.HYP.0000153462.06604.5d
10.1002/iub.1247
10.1007/s00210-007-0200-8
10.1124/dmd.110.035287
10.1073/pnas.0437829100
10.1096/fj.10-171488
10.1074/jbc.271.7.3460
10.1016/j.phrs.2003.09.014
10.1001/jama.2012.28733
10.1002/hep.25846
10.1128/MCB.01482-06
10.1073/pnas.1221972110
10.1093/jn/131.1.39
10.2174/1389200033336900
10.1002/ijc.1517
10.1172/JCI59176
10.1124/jpet.109.152017
10.1093/cvr/cvu015
10.1038/ejcn.2013.197
10.1038/nature05883
10.1093/emboj/18.20.5494
10.1161/01.RES.81.2.258
10.1172/JCI34260
10.1161/01.CIR.0000143832.91812.60
10.1158/0008-5472.CAN-04-4173
10.1182/blood-2007-11-126680
10.1007/s10555-010-9264-x
10.1113/jphysiol.2011.215533
10.1016/j.prostaglandins.2006.05.004
10.1073/pnas.261710799
10.1074/jbc.M008106200
10.1155/2013/743171
10.1016/j.prostaglandins.2006.07.001
10.1074/jbc.M305385200
10.1016/j.plefa.2013.04.001
10.1152/ajprenal.00301.2005
10.1016/0006-291X(87)90576-6
10.1016/0006-291X(83)90843-4
10.1016/j.atherosclerosis.2006.11.001
10.1182/blood-2008-03-145219
10.1186/1744-8069-7-78
10.1038/nm1168
10.1074/jbc.M708821200
10.1016/j.ejps.2010.03.018
10.1038/sj.bjp.0704776
10.1089/scd.2010.0098
10.1038/46816
10.1096/fasebj.14.2.255
10.1016/j.prostaglandins.2012.12.001
10.1007/s00018-007-7308-3
10.1093/hmg/ddl085
10.1152/ajpcell.00402.2006
10.1194/jlr.M047357
10.1016/j.bbrc.2005.03.171
10.1161/01.RES.0000015328.20581.D6
10.3109/03602532.2012.754460
10.1006/abbi.1993.1411
10.1073/pnas.081627898
10.1152/ajplung.00150.2003
10.1152/ajpheart.00648.2011
10.1016/S0304-4165(02)00492-0
10.1152/ajpheart.2000.278.4.H1163
10.1093/jnci/djg108
10.1073/pnas.1206493109
10.1161/01.RES.0000018162.87285.F8
10.1093/ajcn/84.1.5
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References Shivachar (2019081415431882000_66.4.1106.328) 1995; 65
2019081415431882000_66.4.1106.313
2019081415431882000_66.4.1106.434
2019081415431882000_66.4.1106.312
2019081415431882000_66.4.1106.315
2019081415431882000_66.4.1106.314
2019081415431882000_66.4.1106.317
2019081415431882000_66.4.1106.316
2019081415431882000_66.4.1106.319
2019081415431882000_66.4.1106.318
2019081415431882000_66.4.1106.311
2019081415431882000_66.4.1106.432
2019081415431882000_66.4.1106.310
2019081415431882000_66.4.1106.309
2019081415431882000_66.4.1106.302
2019081415431882000_66.4.1106.423
2019081415431882000_66.4.1106.301
2019081415431882000_66.4.1106.422
2019081415431882000_66.4.1106.304
2019081415431882000_66.4.1106.425
2019081415431882000_66.4.1106.303
2019081415431882000_66.4.1106.424
2019081415431882000_66.4.1106.306
2019081415431882000_66.4.1106.427
2019081415431882000_66.4.1106.305
2019081415431882000_66.4.1106.426
2019081415431882000_66.4.1106.308
2019081415431882000_66.4.1106.429
2019081415431882000_66.4.1106.307
2019081415431882000_66.4.1106.428
2019081415431882000_66.4.1106.300
2019081415431882000_66.4.1106.421
Chaudhary (2019081415431882000_66.4.1106.53) 2013; 104-105
2019081415431882000_66.4.1106.420
2019081415431882000_66.4.1106.419
2019081415431882000_66.4.1106.412
2019081415431882000_66.4.1106.411
2019081415431882000_66.4.1106.414
2019081415431882000_66.4.1106.413
2019081415431882000_66.4.1106.416
2019081415431882000_66.4.1106.415
2019081415431882000_66.4.1106.417
2019081415431882000_66.4.1106.410
Coon (2019081415431882000_66.4.1106.75) 1992; 6
2019081415431882000_66.4.1106.409
2019081415431882000_66.4.1106.408
2019081415431882000_66.4.1106.401
2019081415431882000_66.4.1106.400
2019081415431882000_66.4.1106.403
2019081415431882000_66.4.1106.402
2019081415431882000_66.4.1106.405
2019081415431882000_66.4.1106.404
2019081415431882000_66.4.1106.407
2019081415431882000_66.4.1106.406
Shena (2019081415431882000_66.4.1106.326) 2014; 395
Pascual (2019081415431882000_66.4.1106.283) 1998; 286
Cazade (2019081415431882000_66.4.1106.49) 2013; 466
2019081415431882000_66.4.1106.115
2019081415431882000_66.4.1106.236
2019081415431882000_66.4.1106.357
2019081415431882000_66.4.1106.114
2019081415431882000_66.4.1106.235
2019081415431882000_66.4.1106.356
2019081415431882000_66.4.1106.117
2019081415431882000_66.4.1106.238
2019081415431882000_66.4.1106.359
2019081415431882000_66.4.1106.116
2019081415431882000_66.4.1106.358
2019081415431882000_66.4.1106.118
2019081415431882000_66.4.1106.239
2019081415431882000_66.4.1106.230
2019081415431882000_66.4.1106.351
2019081415431882000_66.4.1106.350
2019081415431882000_66.4.1106.111
2019081415431882000_66.4.1106.232
2019081415431882000_66.4.1106.353
2019081415431882000_66.4.1106.110
2019081415431882000_66.4.1106.231
2019081415431882000_66.4.1106.352
2019081415431882000_66.4.1106.113
2019081415431882000_66.4.1106.234
2019081415431882000_66.4.1106.355
2019081415431882000_66.4.1106.112
2019081415431882000_66.4.1106.233
2019081415431882000_66.4.1106.354
Devlin (2019081415431882000_66.4.1106.88) 2010; 49
Marill (2019081415431882000_66.4.1106.237) 2003; 4
2019081415431882000_66.4.1106.104
2019081415431882000_66.4.1106.225
2019081415431882000_66.4.1106.346
2019081415431882000_66.4.1106.103
2019081415431882000_66.4.1106.224
2019081415431882000_66.4.1106.345
2019081415431882000_66.4.1106.106
2019081415431882000_66.4.1106.227
2019081415431882000_66.4.1106.348
2019081415431882000_66.4.1106.105
2019081415431882000_66.4.1106.226
2019081415431882000_66.4.1106.108
2019081415431882000_66.4.1106.229
2019081415431882000_66.4.1106.107
2019081415431882000_66.4.1106.228
2019081415431882000_66.4.1106.349
2019081415431882000_66.4.1106.109
2019081415431882000_66.4.1106.100
2019081415431882000_66.4.1106.221
2019081415431882000_66.4.1106.342
2019081415431882000_66.4.1106.220
2019081415431882000_66.4.1106.102
2019081415431882000_66.4.1106.223
2019081415431882000_66.4.1106.344
2019081415431882000_66.4.1106.101
2019081415431882000_66.4.1106.222
2019081415431882000_66.4.1106.343
2019081415431882000_66.4.1106.214
2019081415431882000_66.4.1106.335
2019081415431882000_66.4.1106.213
2019081415431882000_66.4.1106.334
Tanaka (2019081415431882000_66.4.1106.347) 2008; 1779
2019081415431882000_66.4.1106.216
2019081415431882000_66.4.1106.337
2019081415431882000_66.4.1106.215
2019081415431882000_66.4.1106.336
2019081415431882000_66.4.1106.218
2019081415431882000_66.4.1106.339
2019081415431882000_66.4.1106.217
2019081415431882000_66.4.1106.338
2019081415431882000_66.4.1106.219
2019081415431882000_66.4.1106.210
2019081415431882000_66.4.1106.331
2019081415431882000_66.4.1106.330
Zhang (2019081415431882000_66.4.1106.418) 2010; 1799
2019081415431882000_66.4.1106.333
2019081415431882000_66.4.1106.211
2019081415431882000_66.4.1106.332
Hashimoto (2019081415431882000_66.4.1106.150) 1999; 129
Karara (2019081415431882000_66.4.1106.185) 1991; 266
2019081415431882000_66.4.1106.203
2019081415431882000_66.4.1106.324
2019081415431882000_66.4.1106.202
2019081415431882000_66.4.1106.323
2019081415431882000_66.4.1106.205
2019081415431882000_66.4.1106.204
2019081415431882000_66.4.1106.325
2019081415431882000_66.4.1106.207
2019081415431882000_66.4.1106.206
2019081415431882000_66.4.1106.327
2019081415431882000_66.4.1106.329
2019081415431882000_66.4.1106.320
2019081415431882000_66.4.1106.201
2019081415431882000_66.4.1106.322
2019081415431882000_66.4.1106.200
2019081415431882000_66.4.1106.321
2019081415431882000_66.4.1106.48
2019081415431882000_66.4.1106.45
2019081415431882000_66.4.1106.159
2019081415431882000_66.4.1106.44
2019081415431882000_66.4.1106.158
2019081415431882000_66.4.1106.279
2019081415431882000_66.4.1106.47
2019081415431882000_66.4.1106.40
2019081415431882000_66.4.1106.43
2019081415431882000_66.4.1106.42
2019081415431882000_66.4.1106.151
2019081415431882000_66.4.1106.272
2019081415431882000_66.4.1106.393
2019081415431882000_66.4.1106.271
2019081415431882000_66.4.1106.392
2019081415431882000_66.4.1106.50
2019081415431882000_66.4.1106.153
2019081415431882000_66.4.1106.274
2019081415431882000_66.4.1106.395
2019081415431882000_66.4.1106.152
2019081415431882000_66.4.1106.273
2019081415431882000_66.4.1106.394
2019081415431882000_66.4.1106.155
2019081415431882000_66.4.1106.276
2019081415431882000_66.4.1106.397
2019081415431882000_66.4.1106.154
2019081415431882000_66.4.1106.275
2019081415431882000_66.4.1106.396
2019081415431882000_66.4.1106.157
2019081415431882000_66.4.1106.278
2019081415431882000_66.4.1106.399
2019081415431882000_66.4.1106.156
2019081415431882000_66.4.1106.277
2019081415431882000_66.4.1106.398
2019081415431882000_66.4.1106.270
2019081415431882000_66.4.1106.391
2019081415431882000_66.4.1106.390
2019081415431882000_66.4.1106.37
2019081415431882000_66.4.1106.39
2019081415431882000_66.4.1106.34
2019081415431882000_66.4.1106.148
2019081415431882000_66.4.1106.269
2019081415431882000_66.4.1106.33
2019081415431882000_66.4.1106.147
2019081415431882000_66.4.1106.268
2019081415431882000_66.4.1106.389
2019081415431882000_66.4.1106.36
2019081415431882000_66.4.1106.35
2019081415431882000_66.4.1106.149
2019081415431882000_66.4.1106.30
2019081415431882000_66.4.1106.32
2019081415431882000_66.4.1106.31
2019081415431882000_66.4.1106.140
2019081415431882000_66.4.1106.261
2019081415431882000_66.4.1106.382
2019081415431882000_66.4.1106.260
2019081415431882000_66.4.1106.381
2019081415431882000_66.4.1106.142
2019081415431882000_66.4.1106.263
2019081415431882000_66.4.1106.384
2019081415431882000_66.4.1106.141
2019081415431882000_66.4.1106.262
2019081415431882000_66.4.1106.383
2019081415431882000_66.4.1106.144
2019081415431882000_66.4.1106.265
2019081415431882000_66.4.1106.386
2019081415431882000_66.4.1106.143
2019081415431882000_66.4.1106.385
2019081415431882000_66.4.1106.146
2019081415431882000_66.4.1106.267
2019081415431882000_66.4.1106.388
2019081415431882000_66.4.1106.145
2019081415431882000_66.4.1106.266
2019081415431882000_66.4.1106.387
2019081415431882000_66.4.1106.380
Stone (2019081415431882000_66.4.1106.341) 1995; 15
Imig (2019081415431882000_66.4.1106.167) 2013; 104-105
2019081415431882000_66.4.1106.67
2019081415431882000_66.4.1106.137
2019081415431882000_66.4.1106.258
2019081415431882000_66.4.1106.379
2019081415431882000_66.4.1106.66
2019081415431882000_66.4.1106.257
2019081415431882000_66.4.1106.378
2019081415431882000_66.4.1106.69
2019081415431882000_66.4.1106.139
2019081415431882000_66.4.1106.68
2019081415431882000_66.4.1106.138
2019081415431882000_66.4.1106.259
2019081415431882000_66.4.1106.63
2019081415431882000_66.4.1106.62
2019081415431882000_66.4.1106.65
2019081415431882000_66.4.1106.70
2019081415431882000_66.4.1106.250
2019081415431882000_66.4.1106.371
2019081415431882000_66.4.1106.370
2019081415431882000_66.4.1106.72
2019081415431882000_66.4.1106.131
2019081415431882000_66.4.1106.252
2019081415431882000_66.4.1106.373
2019081415431882000_66.4.1106.71
2019081415431882000_66.4.1106.130
2019081415431882000_66.4.1106.251
2019081415431882000_66.4.1106.133
2019081415431882000_66.4.1106.254
Titos (2019081415431882000_66.4.1106.360) 1999; 277
2019081415431882000_66.4.1106.132
2019081415431882000_66.4.1106.253
2019081415431882000_66.4.1106.374
2019081415431882000_66.4.1106.135
2019081415431882000_66.4.1106.256
2019081415431882000_66.4.1106.377
2019081415431882000_66.4.1106.376
2019081415431882000_66.4.1106.59
2019081415431882000_66.4.1106.56
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2019081415431882000_66.4.1
References_xml – ident: 2019081415431882000_66.4.1106.311
  doi: 10.1089/ars.2013.5466
– ident: 2019081415431882000_66.4.1106.166
  doi: 10.1152/physrev.00021.2011
– ident: 2019081415431882000_66.4.1106.227
  doi: 10.1152/ajpendo.00131.2009
– ident: 2019081415431882000_66.4.1106.12
  doi: 10.3390/ijms141123086
– ident: 2019081415431882000_66.4.1106.163
  doi: 10.1042/CS20130479
– ident: 2019081415431882000_66.4.1106.138
  doi: 10.1016/j.cell.2009.01.015
– ident: 2019081415431882000_66.4.1106.420
  doi: 10.1073/pnas.1304321110
– ident: 2019081415431882000_66.4.1106.37
  doi: 10.1006/abio.1998.2897
– ident: 2019081415431882000_66.4.1106.367
  doi: 10.1016/j.prostaglandins.2011.07.005
– ident: 2019081415431882000_66.4.1106.62
  doi: 10.1074/jbc.M709873200
– ident: 2019081415431882000_66.4.1106.261
  doi: 10.1016/0166-2236(96)10040-0
– ident: 2019081415431882000_66.4.1106.109
  doi: 10.1021/jm200132q
– ident: 2019081415431882000_66.4.1106.428
  doi: 10.1371/journal.pone.0083310
– ident: 2019081415431882000_66.4.1106.144
  doi: 10.1016/j.yjmcc.2013.02.003
– ident: 2019081415431882000_66.4.1106.334
  doi: 10.1016/S0140-6736(03)13081-4
– ident: 2019081415431882000_66.4.1106.238
  doi: 10.1016/0014-2999(95)00861-6
– ident: 2019081415431882000_66.4.1106.77
  doi: 10.1016/j.jtcvs.2013.03.015
– ident: 2019081415431882000_66.4.1106.244
  doi: 10.1242/jcs.02674
– ident: 2019081415431882000_66.4.1106.280
  doi: 10.1172/JCI58128
– ident: 2019081415431882000_66.4.1106.8
  doi: 10.1089/ars.2013.5473
– ident: 2019081415431882000_66.4.1106.111
  doi: 10.1152/ajpheart.00427.2005
– ident: 2019081415431882000_66.4.1106.204
  doi: 10.1016/j.ceca.2009.02.007
– ident: 2019081415431882000_66.4.1106.258
  doi: 10.1002/(SICI)1096-9888(199708)32:8<888::AID-JMS548>3.0.CO;2-W
– ident: 2019081415431882000_66.4.1106.39
  doi: 10.1371/journal.pone.0026591
– ident: 2019081415431882000_66.4.1106.45
  doi: 10.1097/MNH.0b013e32835d911e
– ident: 2019081415431882000_66.4.1106.276
  doi: 10.1007/BF02522457
– ident: 2019081415431882000_66.4.1106.432
  doi: 10.1016/j.pharmthera.2009.12.002
– ident: 2019081415431882000_66.4.1106.225
  doi: 10.1124/jpet.110.167544
– ident: 2019081415431882000_66.4.1106.274
  doi: 10.1016/j.cell.2010.07.041
– ident: 2019081415431882000_66.4.1106.7
  doi: 10.1074/jbc.M110.118406
– ident: 2019081415431882000_66.4.1106.333
  doi: 10.1158/1541-7786.MCR-05-0101
– ident: 2019081415431882000_66.4.1106.291
  doi: 10.1016/j.bbrc.2011.06.132
– ident: 2019081415431882000_66.4.1106.277
  doi: 10.1161/CIRCULATIONAHA.110.990317
– ident: 2019081415431882000_66.4.1106.413
  doi: 10.1152/ajpheart.00318.2005
– ident: 2019081415431882000_66.4.1106.24
  doi: 10.1152/ajpheart.01079.2005
– ident: 2019081415431882000_66.4.1106.234
  doi: 10.1016/j.tips.2008.05.003
– ident: 2019081415431882000_66.4.1106.254
  doi: 10.1016/S0002-9440(10)63142-2
– ident: 2019081415431882000_66.4.1106.58
  doi: 10.1371/journal.pone.0039197
– ident: 2019081415431882000_66.4.1106.149
  doi: 10.1016/j.gene.2013.05.008
– ident: 2019081415431882000_66.4.1106.406
  doi: 10.1124/mol.60.2.310
– ident: 2019081415431882000_66.4.1106.298
  doi: 10.1074/jbc.M501730200
– ident: 2019081415431882000_66.4.1106.22
  doi: 10.1124/jpet.108.145102
– ident: 2019081415431882000_66.4.1106.313
  doi: 10.1007/s10038-003-0103-6
– volume: 270
  start-page: F822
  year: 1996
  ident: 2019081415431882000_66.4.1106.433
  article-title: Stereospecific effects of epoxyeicosatrienoic acids on renal vascular tone and K(+)-channel activity
  publication-title: Am J Physiol
  contributor:
    fullname: Zou
– ident: 2019081415431882000_66.4.1106.332
  doi: 10.1523/JNEUROSCI.5793-11.2012
– ident: 2019081415431882000_66.4.1106.387
  doi: 10.1161/ATVBAHA.107.161190
– ident: 2019081415431882000_66.4.1106.145
  doi: 10.1124/jpet.111.179036
– ident: 2019081415431882000_66.4.1106.352
  doi: 10.1111/j.1365-2710.2009.01146.x
– ident: 2019081415431882000_66.4.1106.364
  doi: 10.1111/j.1476-5381.2011.01641.x
– ident: 2019081415431882000_66.4.1106.243
  doi: 10.1016/j.jnutbio.2014.02.004
– ident: 2019081415431882000_66.4.1106.222
  doi: 10.1097/MCO.0b013e32835c5f29
– ident: 2019081415431882000_66.4.1106.188
  doi: 10.1038/ki.2013.187
– ident: 2019081415431882000_66.4.1106.312
  doi: 10.1152/ajpheart.00001.2013
– ident: 2019081415431882000_66.4.1106.296
  doi: 10.1074/jbc.M110806200
– volume: 284
  start-page: 51
  year: 1998
  ident: 2019081415431882000_66.4.1106.38
  article-title: Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes
  publication-title: J Pharmacol Exp Ther
  contributor:
    fullname: Bylund
– ident: 2019081415431882000_66.4.1106.210
  doi: 10.1111/j.1528-1157.1995.tb01645.x
– ident: 2019081415431882000_66.4.1106.124
  doi: 10.1093/hmg/ddi315
– ident: 2019081415431882000_66.4.1106.184
  doi: 10.1371/journal.pone.0011979
– ident: 2019081415431882000_66.4.1106.282
  doi: 10.1074/jbc.M110299200
– volume: 1799
  start-page: 659
  year: 2010
  ident: 2019081415431882000_66.4.1106.418
  article-title: DNA methylation of the promoter of soluble epoxide hydrolase silences its expression by an SP-1-dependent mechanism
  publication-title: Biochim Biophys Acta
  doi: 10.1016/j.bbagrm.2010.09.006
  contributor:
    fullname: Zhang
– ident: 2019081415431882000_66.4.1106.415
  doi: 10.1016/j.cccn.2004.04.028
– ident: 2019081415431882000_66.4.1106.201
  doi: 10.1016/S0009-8981(00)00264-3
– volume: 266
  start-page: 7561
  year: 1991
  ident: 2019081415431882000_66.4.1106.185
  article-title: Endogenous epoxyeicosatrienoyl-phospholipids. A novel class of cellular glycerolipids containing epoxidized arachidonate moieties
  publication-title: J Biol Chem
  doi: 10.1016/S0021-9258(20)89484-8
  contributor:
    fullname: Karara
– ident: 2019081415431882000_66.4.1106.315
  doi: 10.1016/j.prostaglandins.2010.12.001
– volume: 29
  start-page: 242
  year: 2001
  ident: 2019081415431882000_66.4.1106.136
  article-title: Induction of CYP2C genes in human hepatocytes in primary culture
  publication-title: Drug Metab Dispos
  contributor:
    fullname: Gerbal-Chaloin
– ident: 2019081415431882000_66.4.1106.404
  doi: 10.1016/j.addr.2011.03.006
– ident: 2019081415431882000_66.4.1106.417
  doi: 10.1161/01.STR.0000037787.07479.9A
– ident: 2019081415431882000_66.4.1106.289
  doi: 10.1161/01.HYP.0000208299.62535.58
– ident: 2019081415431882000_66.4.1106.52
  doi: 10.1097/FJC.0b013e31827afcee
– ident: 2019081415431882000_66.4.1106.361
  doi: 10.1021/bi050842g
– ident: 2019081415431882000_66.4.1106.112
  doi: 10.1016/S0090-6980(03)00002-9
– ident: 2019081415431882000_66.4.1106.148
  doi: 10.1002/jps.22639
– volume: 6
  start-page: 669
  year: 1992
  ident: 2019081415431882000_66.4.1106.75
  article-title: Cytochrome P450: progress and predictions
  publication-title: FASEB J
  doi: 10.1096/fasebj.6.2.1537454
  contributor:
    fullname: Coon
– ident: 2019081415431882000_66.4.1106.299
  doi: 10.1016/S0891-5849(97)00463-2
– ident: 2019081415431882000_66.4.1106.290
  doi: 10.1111/joim.12016
– ident: 2019081415431882000_66.4.1106.239
  doi: 10.1080/10739680500466400
– ident: 2019081415431882000_66.4.1106.164
  doi: 10.1152/ajprenal.00350.2004
– ident: 2019081415431882000_66.4.1106.295
  doi: 10.1016/j.cell.2011.08.039
– ident: 2019081415431882000_66.4.1106.381
  doi: 10.1124/jpet.105.083477
– ident: 2019081415431882000_66.4.1106.371
  doi: 10.1210/jc.2009-1669
– ident: 2019081415431882000_66.4.1106.26
  doi: 10.1016/j.yjmcc.2009.01.009
– ident: 2019081415431882000_66.4.1106.301
  doi: 10.1161/ATVBAHA.110.204099
– ident: 2019081415431882000_66.4.1106.219
  doi: 10.1073/pnas.0508081102
– ident: 2019081415431882000_66.4.1106.273
  doi: 10.1016/j.cmet.2012.04.009
– ident: 2019081415431882000_66.4.1106.306
  doi: 10.1164/rccm.200806-848OC
– volume: 2013
  start-page: 712949
  year: 2013
  ident: 2019081415431882000_66.4.1106.209
  article-title: Cardioprotective effects of ω -3 PUFAs in chronic kidney disease
  publication-title: Biomed Res Int
  contributor:
    fullname: Lee
– ident: 2019081415431882000_66.4.1106.321
  doi: 10.1021/cr100396c
– ident: 2019081415431882000_66.4.1106.70
  doi: 10.1002/med.10050
– ident: 2019081415431882000_66.4.1106.403
  doi: 10.1210/en.2012-2012
– ident: 2019081415431882000_66.4.1106.410
  doi: 10.1016/j.pharmthera.2013.10.010
– ident: 2019081415431882000_66.4.1106.320
  doi: 10.1096/fj.11-0502ufm
– ident: 2019081415431882000_66.4.1106.286
  doi: 10.1074/jbc.M112.407981
– ident: 2019081415431882000_66.4.1106.197
  doi: 10.1074/jbc.M113.481077
– ident: 2019081415431882000_66.4.1106.272
  doi: 10.1097/MCO.0b013e3283479230
– ident: 2019081415431882000_66.4.1106.104
  doi: 10.1016/j.bbrc.2005.12.180
– ident: 2019081415431882000_66.4.1106.256
  doi: 10.1016/j.immuni.2006.10.015
– ident: 2019081415431882000_66.4.1106.84
  doi: 10.1006/bbrc.1993.1803
– ident: 2019081415431882000_66.4.1106.170
  doi: 10.1016/j.lfs.2006.07.031
– ident: 2019081415431882000_66.4.1106.191
  doi: 10.1096/fj.12-218040
– ident: 2019081415431882000_66.4.1106.235
  doi: 10.1042/BJ20021903
– ident: 2019081415431882000_66.4.1106.265
  doi: 10.1111/j.1349-7006.2010.01713.x
– ident: 2019081415431882000_66.4.1106.13
  doi: 10.1074/jbc.M109.054759
– ident: 2019081415431882000_66.4.1106.226
  doi: 10.1073/pnas.1103482108
– ident: 2019081415431882000_66.4.1106.369
  doi: 10.1074/jbc.271.24.14001
– ident: 2019081415431882000_66.4.1106.374
  doi: 10.1016/j.ejphar.2012.12.015
– ident: 2019081415431882000_66.4.1106.425
  doi: 10.1194/jlr.M017319
– ident: 2019081415431882000_66.4.1106.89
  doi: 10.1021/pr4004739
– ident: 2019081415431882000_66.4.1106.365
  doi: 10.1097/FJC.0b013e318185fa3c
– ident: 2019081415431882000_66.4.1106.335
  doi: 10.1073/pnas.0409591102
– ident: 2019081415431882000_66.4.1106.344
  doi: 10.1681/ASN.2009111110
– ident: 2019081415431882000_66.4.1106.182
  doi: 10.1038/jcbfm.2013.130
– ident: 2019081415431882000_66.4.1106.242
  doi: 10.1021/jm301617j
– ident: 2019081415431882000_66.4.1106.93
  doi: 10.1152/ajpheart.00125.2002
– ident: 2019081415431882000_66.4.1106.173
  doi: 10.1073/pnas.1101073108
– ident: 2019081415431882000_66.4.1106.305
  doi: 10.1196/annals.1375.019
– ident: 2019081415431882000_66.4.1106.107
  doi: 10.1152/ajpheart.00831.2001
– ident: 2019081415431882000_66.4.1106.175
  doi: 10.1007/978-94-007-0265-3_42
– ident: 2019081415431882000_66.4.1106.50
  doi: 10.1387/ijdb.103067cc
– ident: 2019081415431882000_66.4.1106.71
  doi: 10.1016/j.toxlet.2014.02.026
– ident: 2019081415431882000_66.4.1106.82
  doi: 10.1124/jpet.105.091876
– ident: 2019081415431882000_66.4.1106.386
  doi: 10.1152/ajpcell.00230.2008
– ident: 2019081415431882000_66.4.1106.181
  doi: 10.1161/HYPERTENSIONAHA.109.146399
– ident: 2019081415431882000_66.4.1106.285
  doi: 10.1016/B978-0-12-385061-4.00002-7
– ident: 2019081415431882000_66.4.1106.103
  doi: 10.1007/s10735-006-9050-9
– ident: 2019081415431882000_66.4.1106.57
  doi: 10.1124/jpet.110.174805
– ident: 2019081415431882000_66.4.1106.59
  doi: 10.1016/j.prostaglandins.2011.06.009
– ident: 2019081415431882000_66.4.1106.421
  doi: 10.1097/CCM.0000000000000226
– ident: 2019081415431882000_66.4.1106.319
  doi: 10.1016/j.atherosclerosis.2013.01.034
– ident: 2019081415431882000_66.4.1106.223
  doi: 10.1124/mol.62.5.1076
– ident: 2019081415431882000_66.4.1106.389
  doi: 10.1085/jgp.200409140
– volume: 41
  start-page: 163
  year: 2000
  ident: 2019081415431882000_66.4.1106.46
  article-title: Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase
  publication-title: J Lipid Res
  doi: 10.1016/S0022-2275(20)32049-6
  contributor:
    fullname: Capdevila
– ident: 2019081415431882000_66.4.1106.318
  doi: 10.1016/j.plefa.2013.12.008
– ident: 2019081415431882000_66.4.1106.23
  doi: 10.1161/01.HYP.0000246672.72188.bd
– ident: 2019081415431882000_66.4.1106.16
  doi: 10.1016/j.yjmcc.2008.09.711
– ident: 2019081415431882000_66.4.1106.263
  doi: 10.1124/dmd.106.013839
– ident: 2019081415431882000_66.4.1106.397
  doi: 10.1113/expphysiol.2007.038612
– ident: 2019081415431882000_66.4.1106.266
  doi: 10.1126/science.285.5431.1276
– ident: 2019081415431882000_66.4.1106.30
  doi: 10.1161/hy0202.103420
– volume: 284
  start-page: H2153
  year: 2003
  ident: 2019081415431882000_66.4.1106.340
  article-title: Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit
  publication-title: Am J Physiol Heart Circ Physiol
  doi: 10.1152/ajpheart.00844.2002
  contributor:
    fullname: Stephenson
– ident: 2019081415431882000_66.4.1106.380
  doi: 10.1124/mol.113.087122
– ident: 2019081415431882000_66.4.1106.396
  doi: 10.1016/S0090-6980(00)00079-4
– ident: 2019081415431882000_66.4.1106.300
  doi: 10.1097/00003246-199602000-00010
– ident: 2019081415431882000_66.4.1106.9
  doi: 10.1002/path.2611
– ident: 2019081415431882000_66.4.1106.157
  doi: 10.1093/cvr/cvr267
– ident: 2019081415431882000_66.4.1106.392
  doi: 10.1038/sj.bjp.0706256
– ident: 2019081415431882000_66.4.1106.345
  doi: 10.1016/j.bcp.2011.07.100
– ident: 2019081415431882000_66.4.1106.187
  doi: 10.1016/j.yjmcc.2009.02.028
– ident: 2019081415431882000_66.4.1106.409
  doi: 10.1177/1076029610364522
– ident: 2019081415431882000_66.4.1106.373
  doi: 10.1161/01.RES.0000187474.47805.30
– ident: 2019081415431882000_66.4.1106.422
  doi: 10.1161/ATVBAHA.109.186064
– volume: 104-105
  start-page: 2
  year: 2013
  ident: 2019081415431882000_66.4.1106.167
  article-title: Epoxyeicosatrienoic acids, 20-hydroxyeicosatetraenoic acid, and renal microvascular function
  publication-title: Prostaglandins Other Lipid Mediat
  doi: 10.1016/j.prostaglandins.2013.01.002
  contributor:
    fullname: Imig
– ident: 2019081415431882000_66.4.1106.384
  doi: 10.1016/j.bbamem.2008.10.011
– ident: 2019081415431882000_66.4.1106.203
  doi: 10.1021/jm301194c
– ident: 2019081415431882000_66.4.1106.351
  doi: 10.1038/sj.bjp.0702078
– ident: 2019081415431882000_66.4.1106.137
  doi: 10.1016/S1097-2765(00)80342-1
– ident: 2019081415431882000_66.4.1106.169
  doi: 10.1258/ebm.2012.012225
– ident: 2019081415431882000_66.4.1106.342
  doi: 10.1111/j.1549-8719.2012.00202.x
– ident: 2019081415431882000_66.4.1106.186
  doi: 10.1016/j.taap.2004.12.022
– ident: 2019081415431882000_66.4.1106.353
  doi: 10.1124/jpet.108.136739
– ident: 2019081415431882000_66.4.1106.268
  doi: 10.1371/journal.pone.0076575
– ident: 2019081415431882000_66.4.1106.3
  doi: 10.1161/01.STR.0000016332.37292.59
– ident: 2019081415431882000_66.4.1106.128
  doi: 10.1007/s00395-012-0319-8
– ident: 2019081415431882000_66.4.1106.40
  doi: 10.1017/S0029665110000157
– volume: 2012
  start-page: 758614
  year: 2012
  ident: 2019081415431882000_66.4.1106.176
  article-title: Pharmacological inhibition of soluble epoxide hydrolase ameliorates diet-induced metabolic syndrome in rats
  publication-title: Exp Diabetes Res
  doi: 10.1155/2012/758614
  contributor:
    fullname: Iyer
– volume: 283
  start-page: 1479
  year: 1997
  ident: 2019081415431882000_66.4.1106.247
  article-title: Irreversible inhibition of cytochrome P450 by nitric oxide
  publication-title: J Pharmacol Exp Ther
  contributor:
    fullname: Minamiyama
– ident: 2019081415431882000_66.4.1106.43
  doi: 10.1161/01.RES.78.3.415
– ident: 2019081415431882000_66.4.1106.395
  doi: 10.1007/s00424-010-0830-4
– ident: 2019081415431882000_66.4.1106.419
  doi: 10.1161/CIRCRESAHA.111.259325
– ident: 2019081415431882000_66.4.1106.287
  doi: 10.1073/pnas.92.3.905
– ident: 2019081415431882000_66.4.1106.423
  doi: 10.1371/journal.pone.0069913
– ident: 2019081415431882000_66.4.1106.213
  doi: 10.1100/tsw.2010.99
– volume: 1779
  start-page: 17
  year: 2008
  ident: 2019081415431882000_66.4.1106.347
  article-title: Transcriptional regulation of the human soluble epoxide hydrolase gene EPHX2
  publication-title: Biochim Biophys Acta
  doi: 10.1016/j.bbagrm.2007.11.005
  contributor:
    fullname: Tanaka
– ident: 2019081415431882000_66.4.1106.198
  doi: 10.1016/j.bbapap.2010.09.009
– ident: 2019081415431882000_66.4.1106.19
  doi: 10.1161/01.CIR.94.12.3341
– ident: 2019081415431882000_66.4.1106.91
  doi: 10.4049/jimmunol.1300699
– ident: 2019081415431882000_66.4.1106.171
  doi: 10.1073/pnas.0809765105
– ident: 2019081415431882000_66.4.1106.401
  doi: 10.1124/mol.106.023648
– ident: 2019081415431882000_66.4.1106.229
  doi: 10.1210/en.2012-2166
– ident: 2019081415431882000_66.4.1106.34
  doi: 10.1152/ajpheart.01122.2011
– ident: 2019081415431882000_66.4.1106.309
  doi: 10.1016/j.molmed.2012.02.002
– ident: 2019081415431882000_66.4.1106.246
  doi: 10.1016/j.pharmthera.2005.11.003
– ident: 2019081415431882000_66.4.1106.143
  doi: 10.1074/jbc.M110.182329
– ident: 2019081415431882000_66.4.1106.66
  doi: 10.1124/jpet.109.157818
– ident: 2019081415431882000_66.4.1106.29
  doi: 10.1016/0006-2952(94)90235-6
– ident: 2019081415431882000_66.4.1106.252
  doi: 10.1016/j.bbrc.2012.02.108
– ident: 2019081415431882000_66.4.1106.385
  doi: 10.1038/nature01807
– ident: 2019081415431882000_66.4.1106.110
  doi: 10.1124/jpet.105.085605
– ident: 2019081415431882000_66.4.1106.260
  doi: 10.1097/00008571-200401000-00001
– ident: 2019081415431882000_66.4.1106.200
  doi: 10.1016/S0163-7827(02)00002-4
– ident: 2019081415431882000_66.4.1106.411
  doi: 10.1124/jpet.303.2.768
– ident: 2019081415431882000_66.4.1106.271
  doi: 10.1194/jlr.M022319
– ident: 2019081415431882000_66.4.1106.100
  doi: 10.1152/ajpregu.00606.2011
– ident: 2019081415431882000_66.4.1106.121
  doi: 10.1161/hy1201.096532
– ident: 2019081415431882000_66.4.1106.72
  doi: 10.1038/nature02196
– ident: 2019081415431882000_66.4.1106.310
  doi: 10.1038/cddis.2013.418
– ident: 2019081415431882000_66.4.1106.220
  doi: 10.1371/journal.pone.0046065
– ident: 2019081415431882000_66.4.1106.86
  doi: 10.1124/dmd.106.012823
– ident: 2019081415431882000_66.4.1106.377
  doi: 10.1016/j.jjcc.2009.06.004
– ident: 2019081415431882000_66.4.1106.405
  doi: 10.2337/db09-1241
– ident: 2019081415431882000_66.4.1106.221
  doi: 10.1093/cvr/cvn207
– ident: 2019081415431882000_66.4.1106.248
  doi: 10.1074/jbc.M110.198515
– ident: 2019081415431882000_66.4.1106.250
  doi: 10.1038/nm0597-562
– ident: 2019081415431882000_66.4.1106.162
  doi: 10.1161/HYPERTENSIONAHA.113.01949
– ident: 2019081415431882000_66.4.1106.102
  doi: 10.2174/1874073100701010001
– ident: 2019081415431882000_66.4.1106.414
  doi: 10.1007/s004280050359
– volume: 65
  start-page: 338
  year: 1995
  ident: 2019081415431882000_66.4.1106.328
  article-title: Effect of protein kinase C modulators on 14,15-epoxyeicosatrienoic acid incorporation into astroglial phospholipids
  publication-title: J Neurochem
  doi: 10.1046/j.1471-4159.1995.65010338.x
  contributor:
    fullname: Shivachar
– ident: 2019081415431882000_66.4.1106.140
  doi: 10.1073/pnas.0308185100
– ident: 2019081415431882000_66.4.1106.359
  doi: 10.1002/jcb.22709
– ident: 2019081415431882000_66.4.1106.241
  doi: 10.1093/cvr/cvt095
– ident: 2019081415431882000_66.4.1106.245
  doi: 10.1096/fj.02-0640fje
– ident: 2019081415431882000_66.4.1106.217
  doi: 10.1124/jpet.111.180505
– ident: 2019081415431882000_66.4.1106.125
  doi: 10.1517/13543776.2014.899583
– ident: 2019081415431882000_66.4.1106.55
  doi: 10.1111/j.1469-7793.1997.099bi.x
– ident: 2019081415431882000_66.4.1106.81
  doi: 10.1093/carcin/bgu001
– ident: 2019081415431882000_66.4.1106.316
  doi: 10.1021/cr200131e
– ident: 2019081415431882000_66.4.1106.25
  doi: 10.1074/jbc.M113.458414
– ident: 2019081415431882000_66.4.1106.215
  doi: 10.1073/pnas.1011278107
– volume: 49
  start-page: 190
  year: 2010
  ident: 2019081415431882000_66.4.1106.88
  article-title: Cytochrome P450 1B1 mRNA untranslated regions interact to inhibit protein translation
  publication-title: Mol Carcinog
  doi: 10.1002/mc.20589
  contributor:
    fullname: Devlin
– ident: 2019081415431882000_66.4.1106.123
  doi: 10.1161/ATVBAHA.107.152074
– ident: 2019081415431882000_66.4.1106.65
  doi: 10.1021/bi102070w
– ident: 2019081415431882000_66.4.1106.195
  doi: 10.1167/iovs.11-6729
– ident: 2019081415431882000_66.4.1106.240
  doi: 10.1152/ajpheart.01118.2001
– ident: 2019081415431882000_66.4.1106.292
  doi: 10.1113/jphysiol.1996.sp021801
– volume: 129
  start-page: 70
  year: 1999
  ident: 2019081415431882000_66.4.1106.150
  article-title: The hypotensive effect of docosahexaenoic acid is associated with the enhanced release of ATP from the caudal artery of aged rats
  publication-title: J Nutr
  doi: 10.1093/jn/129.1.70
  contributor:
    fullname: Hashimoto
– ident: 2019081415431882000_66.4.1106.424
  doi: 10.1152/ajpheart.00983.2008
– ident: 2019081415431882000_66.4.1106.130
  doi: 10.1124/mol.59.1.16
– ident: 2019081415431882000_66.4.1106.36
  doi: 10.1016/S0165-6147(02)02050-3
– ident: 2019081415431882000_66.4.1106.363
  doi: 10.1158/0008-5472.CAN-06-1403
– ident: 2019081415431882000_66.4.1106.33
  doi: 10.1016/j.taap.2011.12.009
– volume: 104-105
  start-page: 8
  year: 2013
  ident: 2019081415431882000_66.4.1106.53
  article-title: Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice
  publication-title: Prostaglandins Other Lipid Mediat
  doi: 10.1016/j.prostaglandins.2012.08.001
  contributor:
    fullname: Chaudhary
– ident: 2019081415431882000_66.4.1106.427
  doi: 10.1161/JAHA.113.000080
– ident: 2019081415431882000_66.4.1106.101
  doi: 10.1042/CS20130003
– volume: 1088
  start-page: 433
  year: 1991
  ident: 2019081415431882000_66.4.1106.134
  article-title: Isolation of the human cytochrome P-450 IIC8 gene: multiple glucocorticoid responsive elements in the 5′ region
  publication-title: Biochim Biophys Acta
  doi: 10.1016/0167-4781(91)90138-C
  contributor:
    fullname: Ged
– ident: 2019081415431882000_66.4.1106.74
  doi: 10.1007/112_2011_2
– ident: 2019081415431882000_66.4.1106.249
  doi: 10.1016/j.ahj.2010.10.021
– ident: 2019081415431882000_66.4.1106.118
  doi: 10.1161/01.HYP.36.2.270
– ident: 2019081415431882000_66.4.1106.1
  doi: 10.1073/pnas.0703229104
– ident: 2019081415431882000_66.4.1106.15
  doi: 10.1016/j.yjmcc.2012.04.008
– ident: 2019081415431882000_66.4.1106.105
  doi: 10.1074/jbc.M806315200
– ident: 2019081415431882000_66.4.1106.205
  doi: 10.1161/hy0202.103293
– ident: 2019081415431882000_66.4.1106.382
  doi: 10.1152/ajprenal.00038.2008
– ident: 2019081415431882000_66.4.1106.48
  doi: 10.1074/jbc.M113.508416
– ident: 2019081415431882000_66.4.1106.178
  doi: 10.1161/HYPERTENSIONAHA.114.03275
– ident: 2019081415431882000_66.4.1106.228
  doi: 10.1074/jbc.M608057200
– ident: 2019081415431882000_66.4.1106.142
  doi: 10.1006/bbrc.1999.1313
– ident: 2019081415431882000_66.4.1106.434
  doi: 10.1111/j.1476-5381.1996.tb15327.x
– ident: 2019081415431882000_66.4.1106.27
  doi: 10.1111/j.1478-3231.2011.02509.x
– ident: 2019081415431882000_66.4.1106.158
  doi: 10.1084/jem.20131494
– volume: 1841
  start-page: 190
  year: 2014
  ident: 2019081415431882000_66.4.1106.208
  article-title: Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis
  publication-title: Biochim Biophys Acta
  doi: 10.1016/j.bbalip.2013.10.006
  contributor:
    fullname: Lee
– ident: 2019081415431882000_66.4.1106.168
  doi: 10.1038/nrd2875
– volume: 286
  start-page: 772
  year: 1998
  ident: 2019081415431882000_66.4.1106.283
  article-title: Epoxygenase metabolites of arachidonic acid affect electrophysiologic properties of rat tracheal epithelial cells1
  publication-title: J Pharmacol Exp Ther
  contributor:
    fullname: Pascual
– ident: 2019081415431882000_66.4.1106.11
  doi: 10.1074/jbc.M113.525659
– ident: 2019081415431882000_66.4.1106.262
  doi: 10.1073/pnas.0437724100
– ident: 2019081415431882000_66.4.1106.51
  doi: 10.1161/CIRCRESAHA.110.235879
– ident: 2019081415431882000_66.4.1106.161
  doi: 10.1021/jm2001376
– ident: 2019081415431882000_66.4.1106.211
  doi: 10.1161/01.RES.80.6.877
– ident: 2019081415431882000_66.4.1106.177
  doi: 10.1007/s12263-014-0405-7
– ident: 2019081415431882000_66.4.1106.196
  doi: 10.1016/j.plefa.2012.06.001
– ident: 2019081415431882000_66.4.1106.73
  doi: 10.1046/j.1440-1681.2003.03921.x
– ident: 2019081415431882000_66.4.1106.202
  doi: 10.1007/s00424-013-1356-3
– ident: 2019081415431882000_66.4.1106.153
  doi: 10.1113/jphysiol.2002.030833
– ident: 2019081415431882000_66.4.1106.159
  doi: 10.1016/j.resuscitation.2007.06.031
– volume: 466
  start-page: 1759
  year: 2013
  ident: 2019081415431882000_66.4.1106.49
  article-title: 5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone.
  publication-title: Pflugers Arch
  doi: 10.1007/s00424-013-1411-0
  contributor:
    fullname: Cazade
– volume: 412
  start-page: 66
  year: 2011
  ident: 2019081415431882000_66.4.1106.212
  article-title: Identification of miR-130a, miR-27b and miR-210 as serum biomarkers for atherosclerosis obliterans
  publication-title: Biomed Res Int
  contributor:
    fullname: Li
– ident: 2019081415431882000_66.4.1106.199
  doi: 10.1006/abbi.1999.1138
– ident: 2019081415431882000_66.4.1106.376
  doi: 10.1055/s-0029-1243604
– ident: 2019081415431882000_66.4.1106.336
  doi: 10.1124/jpet.109.157545
– ident: 2019081415431882000_66.4.1106.67
  doi: 10.1038/ng.389
– ident: 2019081415431882000_66.4.1106.115
  doi: 10.1161/01.CIR.0000105763.51286.7F
– ident: 2019081415431882000_66.4.1106.129
  doi: 10.1007/978-1-60761-500-2_12
– ident: 2019081415431882000_66.4.1106.14
  doi: 10.1016/j.bbrc.2005.02.103
– ident: 2019081415431882000_66.4.1106.230
  doi: 10.3109/08037051.2010.542640
– ident: 2019081415431882000_66.4.1106.279
  doi: 10.1111/j.1440-1681.2011.05492.x
– ident: 2019081415431882000_66.4.1106.357
  doi: 10.1016/0006-2952(89)90528-5
– ident: 2019081415431882000_66.4.1106.322
  doi: 10.1161/01.RES.0000139436.89654.c8
– volume: 267
  start-page: 15765
  year: 1992
  ident: 2019081415431882000_66.4.1106.98
  article-title: Hormone- and substrate-regulated intracellular degradation of cytochrome P450 (2E1) involving MgATP-activated rapid proteolysis in the endoplasmic reticulum membranes
  publication-title: J Biol Chem
  doi: 10.1016/S0021-9258(19)49601-4
  contributor:
    fullname: Eliasson
– ident: 2019081415431882000_66.4.1106.398
  doi: 10.1371/journal.pone.0007421
– ident: 2019081415431882000_66.4.1106.17
  doi: 10.1139/y2012-082
– ident: 2019081415431882000_66.4.1106.393
  doi: 10.1016/j.prostaglandins.2011.09.001
– ident: 2019081415431882000_66.4.1106.97
  doi: 10.1097/MCO.0b013e3283439622
– ident: 2019081415431882000_66.4.1106.214
  doi: 10.1016/j.nutres.2013.07.004
– ident: 2019081415431882000_66.4.1106.152
  doi: 10.1007/s00441-012-1485-6
– ident: 2019081415431882000_66.4.1106.190
  doi: 10.1093/cvr/cvp281
– ident: 2019081415431882000_66.4.1106.151
  doi: 10.1097/00005344-199810000-00018
– ident: 2019081415431882000_66.4.1106.323
  doi: 10.1016/j.prostaglandins.2006.05.017
– ident: 2019081415431882000_66.4.1106.394
  doi: 10.1016/j.bpj.2012.06.016
– ident: 2019081415431882000_66.4.1106.278
  doi: 10.1152/ajpcell.00139.2013
– ident: 2019081415431882000_66.4.1106.297
  doi: 10.1074/jbc.M701429200
– ident: 2019081415431882000_66.4.1106.231
  doi: 10.1124/dmd.112.046466
– ident: 2019081415431882000_66.4.1106.233
  doi: 10.1152/ajprenal.00098.2009
– volume: 259
  start-page: 5776
  year: 1984
  ident: 2019081415431882000_66.4.1106.368
  article-title: Oxidation of docosahexaenoic acid by rat liver microsomes
  publication-title: J Biol Chem
  doi: 10.1016/S0021-9258(18)91081-1
  contributor:
    fullname: VanRollins
– ident: 2019081415431882000_66.4.1106.78
  doi: 10.1074/jbc.M201575200
– ident: 2019081415431882000_66.4.1106.165
  doi: 10.1097/FJC.0b013e3181e96e0c
– ident: 2019081415431882000_66.4.1106.356
  doi: 10.1016/j.atherosclerosis.2012.03.022
– ident: 2019081415431882000_66.4.1106.54
  doi: 10.1111/j.1469-7793.1998.561bq.x
– ident: 2019081415431882000_66.4.1106.194
  doi: 10.1182/blood-2009-09-243139
– ident: 2019081415431882000_66.4.1106.267
  doi: 10.1074/jbc.M100439200
– volume: 15
  start-page: 4738
  year: 1995
  ident: 2019081415431882000_66.4.1106.341
  article-title: Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia
  publication-title: J Neurosci
  doi: 10.1523/JNEUROSCI.15-07-04738.1995
  contributor:
    fullname: Stone
– ident: 2019081415431882000_66.4.1106.304
  doi: 10.1007/s11745-013-3774-6
– ident: 2019081415431882000_66.4.1106.412
  doi: 10.1152/ajpheart.00423.2004
– ident: 2019081415431882000_66.4.1106.10
  doi: 10.1016/j.biochi.2013.11.006
– ident: 2019081415431882000_66.4.1106.2
  doi: 10.1073/pnas.0811022106
– ident: 2019081415431882000_66.4.1106.303
  doi: 10.3109/08977199709021522
– ident: 2019081415431882000_66.4.1106.407
  doi: 10.1016/j.abb.2009.05.006
– ident: 2019081415431882000_66.4.1106.18
  doi: 10.1016/S0008-6363(02)00257-2
– ident: 2019081415431882000_66.4.1106.42
  doi: 10.1007/s00424-010-0804-6
– ident: 2019081415431882000_66.4.1106.355
  doi: 10.1152/ajpendo.00370.2011
– ident: 2019081415431882000_66.4.1106.180
  doi: 10.1158/0008-5472.CAN-06-3643
– ident: 2019081415431882000_66.4.1106.63
  doi: 10.1124/jpet.113.210120
– ident: 2019081415431882000_66.4.1106.324
  doi: 10.1161/ATVBAHA.113.302927
– ident: 2019081415431882000_66.4.1106.236
  doi: 10.1161/JAHA.112.005033
– ident: 2019081415431882000_66.4.1106.349
  doi: 10.1152/ajpcell.00153.2009
– ident: 2019081415431882000_66.4.1106.95
  doi: 10.1038/24388
– ident: 2019081415431882000_66.4.1106.399
  doi: 10.1038/onc.2013.264
– ident: 2019081415431882000_66.4.1106.147
  doi: 10.1002/cmdc.201100433
– ident: 2019081415431882000_66.4.1106.224
  doi: 10.1113/jphysiol.2006.113985
– ident: 2019081415431882000_66.4.1106.251
  doi: 10.1152/ajplung.90436.2008
– ident: 2019081415431882000_66.4.1106.146
  doi: 10.1016/j.clnu.2010.07.011
– ident: 2019081415431882000_66.4.1106.232
  doi: 10.1146/annurev-nutr-010411-095239
– ident: 2019081415431882000_66.4.1106.44
  doi: 10.1152/ajpheart.00516.2005
– ident: 2019081415431882000_66.4.1106.366
  doi: 10.1097/FJC.0b013e318298e460
– ident: 2019081415431882000_66.4.1106.408
  doi: 10.1124/jpet.107.129577
– ident: 2019081415431882000_66.4.1106.94
  doi: 10.1096/fj.11-188300
– ident: 2019081415431882000_66.4.1106.174
  doi: 10.1254/jphs.12079FP
– volume: 2
  start-page: 1981
  year: 2012
  ident: 2019081415431882000_66.4.1106.264
  article-title: Gap junctions
  publication-title: Compr Physiol
  doi: 10.1002/cphy.c110051
  contributor:
    fullname: Nielsen
– ident: 2019081415431882000_66.4.1106.189
  doi: 10.1096/fj.08-112821
– ident: 2019081415431882000_66.4.1106.416
  doi: 10.1161/01.RES.87.11.992
– ident: 2019081415431882000_66.4.1106.426
  doi: 10.1152/ajpregu.00018.2004
– ident: 2019081415431882000_66.4.1106.80
  doi: 10.1016/S0163-7827(03)00038-9
– ident: 2019081415431882000_66.4.1106.302
  doi: 10.1124/mol.61.2.255
– volume: 279
  start-page: H1526
  year: 2000
  ident: 2019081415431882000_66.4.1106.430
  article-title: Hypoxic pulmonary vasoconstriction is modified by P-450 metabolites
  publication-title: Am J Physiol Heart Circ Physiol
  doi: 10.1152/ajpheart.2000.279.4.H1526
  contributor:
    fullname: Zhu
– ident: 2019081415431882000_66.4.1106.96
  doi: 10.1038/sj.bjp.0703188
– ident: 2019081415431882000_66.4.1106.69
  doi: 10.1097/FJC.0b013e3181506445
– ident: 2019081415431882000_66.4.1106.259
  doi: 10.1016/j.lfs.2008.06.026
– ident: 2019081415431882000_66.4.1106.388
  doi: 10.1016/j.atherosclerosis.2006.02.021
– ident: 2019081415431882000_66.4.1106.284
  doi: 10.1152/ajprenal.00597.2010
– ident: 2019081415431882000_66.4.1106.139
  doi: 10.1016/j.bbrc.2007.01.028
– ident: 2019081415431882000_66.4.1106.135
  doi: 10.1074/jbc.M107228200
– ident: 2019081415431882000_66.4.1106.288
  doi: 10.1007/s13105-013-0303-2
– ident: 2019081415431882000_66.4.1106.257
  doi: 10.1172/JCI27546
– volume: 277
  start-page: C870
  year: 1999
  ident: 2019081415431882000_66.4.1106.360
  article-title: Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4)
  publication-title: Am J Physiol
  doi: 10.1152/ajpcell.1999.277.5.C870
  contributor:
    fullname: Titos
– ident: 2019081415431882000_66.4.1106.160
  doi: 10.1161/01.RES.84.1.53
– ident: 2019081415431882000_66.4.1106.346
  doi: 10.1007/978-1-4899-1813-0_85
– ident: 2019081415431882000_66.4.1106.358
  doi: 10.1007/s12038-007-0028-x
– ident: 2019081415431882000_66.4.1106.92
  doi: 10.1152/ajpheart.01052.2002
– ident: 2019081415431882000_66.4.1106.114
  doi: 10.1016/j.abb.2008.01.002
– volume: 8
  start-page: RA217
  year: 2002
  ident: 2019081415431882000_66.4.1106.372
  article-title: Down-regulation of nuclear receptor DNA-binding activity by nitric oxide—HNF4 as a model system
  publication-title: Med Sci Monit
  contributor:
    fullname: Vossen
– ident: 2019081415431882000_66.4.1106.113
  doi: 10.1007/s11883-013-0389-6
– volume: 278
  start-page: L335
  year: 2000
  ident: 2019081415431882000_66.4.1106.431
  article-title: Epoxyeicosatrienoic acids constrict isolated pressurized rabbit pulmonary arteries
  publication-title: Am J Physiol Lung Cell Mol Physiol
  doi: 10.1152/ajplung.2000.278.2.L335
  contributor:
    fullname: Zhu
– ident: 2019081415431882000_66.4.1106.106
  doi: 10.1021/jm900634w
– ident: 2019081415431882000_66.4.1106.307
  doi: 10.1016/j.taap.2004.12.027
– ident: 2019081415431882000_66.4.1106.327
  doi: 10.1006/dbio.2000.9957
– ident: 2019081415431882000_66.4.1106.35
  doi: 10.1161/HYPERTENSIONAHA.110.151423
– ident: 2019081415431882000_66.4.1106.192
  doi: 10.1007/s13318-011-0024-2
– ident: 2019081415431882000_66.4.1106.20
  doi: 10.1016/j.vph.2009.08.003
– ident: 2019081415431882000_66.4.1106.156
  doi: 10.1161/01.ATV.19.3.680
– ident: 2019081415431882000_66.4.1106.116
  doi: 10.1016/j.ejheart.2007.05.005
– volume: 395
  start-page: 443
  year: 2014
  ident: 2019081415431882000_66.4.1106.326
  article-title: A potent soluble epoxide hydrolase inhibitor, t-AUCB, modulates cholesterol balance and oxidized low density lipoprotein metabolism in adipocytes in vitro
  publication-title: Biol Chem
  doi: 10.1515/hsz-2013-0251
  contributor:
    fullname: Shena
– ident: 2019081415431882000_66.4.1106.216
  doi: 10.1016/j.bcp.2009.10.025
– ident: 2019081415431882000_66.4.1106.85
  doi: 10.1038/oby.2009.227
– ident: 2019081415431882000_66.4.1106.343
  doi: 10.1161/HYPERTENSIONAHA.111.178475
– ident: 2019081415431882000_66.4.1106.90
  doi: 10.1124/jpet.114.214254
– ident: 2019081415431882000_66.4.1106.402
  doi: 10.1124/mol.104.004150
– ident: 2019081415431882000_66.4.1106.379
  doi: 10.1007/s00232-008-9145-1
– ident: 2019081415431882000_66.4.1106.183
  doi: 10.1161/01.HYP.0000153792.29478.1d
– ident: 2019081415431882000_66.4.1106.383
  doi: 10.1016/j.chemphyslip.2008.02.010
– ident: 2019081415431882000_66.4.1106.122
  doi: 10.1161/01.RES.88.1.44
– ident: 2019081415431882000_66.4.1106.61
  doi: 10.1073/pnas.092671899
– ident: 2019081415431882000_66.4.1106.132
  doi: 10.1161/01.HYP.0000153462.06604.5d
– ident: 2019081415431882000_66.4.1106.76
  doi: 10.1002/iub.1247
– ident: 2019081415431882000_66.4.1106.348
  doi: 10.1007/s00210-007-0200-8
– ident: 2019081415431882000_66.4.1106.354
  doi: 10.1124/dmd.110.035287
– ident: 2019081415431882000_66.4.1106.79
  doi: 10.1073/pnas.0437829100
– ident: 2019081415431882000_66.4.1106.87
  doi: 10.1096/fj.10-171488
– ident: 2019081415431882000_66.4.1106.400
  doi: 10.1074/jbc.271.7.3460
– ident: 2019081415431882000_66.4.1106.133
  doi: 10.1016/j.phrs.2003.09.014
– ident: 2019081415431882000_66.4.1106.253
  doi: 10.1001/jama.2012.28733
– ident: 2019081415431882000_66.4.1106.370
  doi: 10.1002/hep.25846
– ident: 2019081415431882000_66.4.1106.60
  doi: 10.1128/MCB.01482-06
– ident: 2019081415431882000_66.4.1106.331
  doi: 10.1073/pnas.1221972110
– volume: 131
  start-page: 39
  year: 2001
  ident: 2019081415431882000_66.4.1106.126
  article-title: A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats
  publication-title: J Nutr
  doi: 10.1093/jn/131.1.39
  contributor:
    fullname: Frenoux
– volume: 4
  start-page: 1
  year: 2003
  ident: 2019081415431882000_66.4.1106.237
  article-title: Retinoic acid metabolism and mechanism of action: a review
  publication-title: Curr Drug Metab
  doi: 10.2174/1389200033336900
  contributor:
    fullname: Marill
– ident: 2019081415431882000_66.4.1106.270
  doi: 10.1002/ijc.1517
– ident: 2019081415431882000_66.4.1106.378
  doi: 10.1172/JCI59176
– ident: 2019081415431882000_66.4.1106.56
  doi: 10.1124/jpet.109.152017
– ident: 2019081415431882000_66.4.1106.99
  doi: 10.1093/cvr/cvu015
– ident: 2019081415431882000_66.4.1106.141
  doi: 10.1038/ejcn.2013.197
– ident: 2019081415431882000_66.4.1106.269
  doi: 10.1038/nature05883
– ident: 2019081415431882000_66.4.1106.6
  doi: 10.1093/emboj/18.20.5494
– ident: 2019081415431882000_66.4.1106.391
  doi: 10.1161/01.RES.81.2.258
– ident: 2019081415431882000_66.4.1106.314
  doi: 10.1172/JCI34260
– ident: 2019081415431882000_66.4.1106.338
  doi: 10.1161/01.CIR.0000143832.91812.60
– ident: 2019081415431882000_66.4.1106.179
  doi: 10.1158/0008-5472.CAN-04-4173
– ident: 2019081415431882000_66.4.1106.68
  doi: 10.1182/blood-2007-11-126680
– ident: 2019081415431882000_66.4.1106.281
  doi: 10.1007/s10555-010-9264-x
– ident: 2019081415431882000_66.4.1106.330
  doi: 10.1113/jphysiol.2011.215533
– ident: 2019081415431882000_66.4.1106.172
  doi: 10.1016/j.prostaglandins.2006.05.004
– ident: 2019081415431882000_66.4.1106.83
  doi: 10.1073/pnas.261710799
– ident: 2019081415431882000_66.4.1106.329
  doi: 10.1074/jbc.M008106200
– volume: 2013
  start-page: 743171
  year: 2013
  ident: 2019081415431882000_66.4.1106.41
  article-title: Experimental evidence of ω-3 polyunsaturated fatty acid modulation of inflammatory cytokines and bioactive lipid mediators: their potential role in inflammatory, neurodegenerative, and neoplastic diseases
  publication-title: Biomed Res Int
  doi: 10.1155/2013/743171
  contributor:
    fullname: Calviello
– ident: 2019081415431882000_66.4.1106.308
  doi: 10.1016/j.prostaglandins.2006.07.001
– ident: 2019081415431882000_66.4.1106.294
  doi: 10.1074/jbc.M305385200
– ident: 2019081415431882000_66.4.1106.317
  doi: 10.1016/j.plefa.2013.04.001
– ident: 2019081415431882000_66.4.1106.390
  doi: 10.1152/ajprenal.00301.2005
– ident: 2019081415431882000_66.4.1106.47
  doi: 10.1016/0006-291X(87)90576-6
– ident: 2019081415431882000_66.4.1106.108
  doi: 10.1016/0006-291X(83)90843-4
– ident: 2019081415431882000_66.4.1106.218
  doi: 10.1016/j.atherosclerosis.2006.11.001
– ident: 2019081415431882000_66.4.1106.350
  doi: 10.1182/blood-2008-03-145219
– ident: 2019081415431882000_66.4.1106.32
  doi: 10.1186/1744-8069-7-78
– ident: 2019081415431882000_66.4.1106.154
  doi: 10.1038/nm1168
– ident: 2019081415431882000_66.4.1106.206
  doi: 10.1074/jbc.M708821200
– ident: 2019081415431882000_66.4.1106.362
  doi: 10.1016/j.ejps.2010.03.018
– ident: 2019081415431882000_66.4.1106.31
  doi: 10.1038/sj.bjp.0704776
– ident: 2019081415431882000_66.4.1106.193
  doi: 10.1089/scd.2010.0098
– ident: 2019081415431882000_66.4.1106.120
  doi: 10.1038/46816
– volume: 14
  start-page: 255
  year: 2000
  ident: 2019081415431882000_66.4.1106.28
  article-title: Antisense oligonucleotides against cytochrome P450 2C8 attenuate EDHF-mediated Ca(2+) changes and dilation in isolated resistance arteries
  publication-title: FASEB J
  doi: 10.1096/fasebj.14.2.255
  contributor:
    fullname: Bolz
– volume: 104-105
  start-page: 42
  year: 2013
  ident: 2019081415431882000_66.4.1106.64
  article-title: Beneficial effects of inhibition of soluble epoxide hydrolase on glucose homeostasis and islet damage in a streptozotocin-induced diabetic mouse model
  publication-title: Prostaglandins Other Lipid Mediat
  doi: 10.1016/j.prostaglandins.2012.12.001
  contributor:
    fullname: Chen
– ident: 2019081415431882000_66.4.1106.325
  doi: 10.1007/s00018-007-7308-3
– ident: 2019081415431882000_66.4.1106.207
  doi: 10.1093/hmg/ddl085
– ident: 2019081415431882000_66.4.1106.337
  doi: 10.1152/ajpcell.00402.2006
– ident: 2019081415431882000_66.4.1106.117
  doi: 10.1194/jlr.M047357
– ident: 2019081415431882000_66.4.1106.275
  doi: 10.1016/j.bbrc.2005.03.171
– ident: 2019081415431882000_66.4.1106.293
  doi: 10.1161/01.RES.0000015328.20581.D6
– ident: 2019081415431882000_66.4.1106.4
  doi: 10.3109/03602532.2012.754460
– ident: 2019081415431882000_66.4.1106.21
  doi: 10.1006/abbi.1993.1411
– ident: 2019081415431882000_66.4.1106.155
  doi: 10.1073/pnas.081627898
– ident: 2019081415431882000_66.4.1106.5
  doi: 10.1152/ajplung.00150.2003
– ident: 2019081415431882000_66.4.1106.429
  doi: 10.1152/ajpheart.00648.2011
– volume: 1619
  start-page: 332
  year: 2003
  ident: 2019081415431882000_66.4.1106.119
  article-title: Cytochrome P450 epoxygenases and vascular tone: novel role for HMG-CoA reductase inhibitors in the regulation of CYP 2C expression
  publication-title: Biochim Biophys Acta
  doi: 10.1016/S0304-4165(02)00492-0
  contributor:
    fullname: Fisslthaler
– volume: 278
  start-page: H1163
  year: 2000
  ident: 2019081415431882000_66.4.1106.255
  article-title: Cerebral microvascular endothelial cell tube formation: role of astrocytic epoxyeicosatrienoic acid release
  publication-title: Am J Physiol Heart Circ Physiol
  doi: 10.1152/ajpheart.2000.278.4.H1163
  contributor:
    fullname: Munzenmaier
– ident: 2019081415431882000_66.4.1106.339
  doi: 10.1093/jnci/djg108
– ident: 2019081415431882000_66.4.1106.127
  doi: 10.1073/pnas.1206493109
– ident: 2019081415431882000_66.4.1106.131
  doi: 10.1161/01.RES.0000018162.87285.F8
– volume: 84
  start-page: 5
  year: 2006
  ident: 2019081415431882000_66.4.1106.375
  article-title: n-3 Fatty acids from fish or fish-oil supplements, but not α-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: a systematic review
  publication-title: Am J Clin Nutr
  doi: 10.1093/ajcn/84.1.5
  contributor:
    fullname: Wang
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Snippet Over the last 20 years, it has become clear that cytochrome P450 (P450) enzymes generate a spectrum of bioactive lipid mediators from endogenous substrates....
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SubjectTerms Animals
Arachidonic Acid - metabolism
Cardiovascular Diseases - physiopathology
Cytochrome P-450 Enzyme System - metabolism
Epoxide Hydrolases - metabolism
Humans
Inflammation - metabolism
Neovascularization, Physiologic - physiology
Title The pharmacology of the cytochrome P450 epoxygenase/soluble epoxide hydrolase axis in the vasculature and cardiovascular disease
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