Modelling and optimization for a switched system in microbial fed-batch culture

• Published in: Applied mathematical modelling Vol. 35; no. 7; pp. 3276 - 3284
• Main Authors: Gong, Zhaohua, Liu, Chongyang, Feng, Enmin, Wang, Lei, Yu, Yongsheng
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Inc 01.07.2011; Elsevier
• Subjects: Applied sciences; Biological and medical sciences; Bioreactors; Biotechnology; Computer science; control theory; systems; Control theory. Systems; Exact sciences and technology; Fed-batch culture; Fermentation; Fermented food industries; Food industries; Fundamental and applied biological sciences. Psychology; Mathematical analysis; Mathematical models; Methods. Procedures. Technologies; Microorganisms; Modelling; Optimization; Process control. Computer integrated manufacturing; Switched system; Switching; Time-scaling transform; Various methods and equipments; Time-scaling transform; Fed-batch culture; Switched system; Optimization; Biotechnology; Multimodel control; Switching function; Fermentation; Modeling; Hybrid system; Smoothing; Inequality constraint; Batch process; State constraint

This paper considers modelling and optimization of a microbial fed-batch fermentation process. A switched system with variable switching instants is proposed to describe the fermentation process of glycerol bioconversion to 1,3-propanediol (1,3-PD). Taking the concentration of 1,3-PD at the terminal...