Exostosin-1/exostosin-2 expression and favorable kidney outcomes in lupus nephritis: a retrospective cohort study

• Published in: Clinical rheumatology Vol. 43; no. 8; pp. 2533 - 2540
• Main Authors: Zavala-Miranda, Maria Fernanda, Sobrino-Vargas, Ana María, Hernández-Andrade, Adriana, Caballero-Malacara, Valeria, Pérez-Arias, Abril A., Márquez-Macedo, Sofía E., Nordmann-Gomes, Alberto, Navarro-Sánchez, Valeria, Juárez-Cuevas, Bernardo, Uribe-Uribe, Norma O., Mejia-Vilet, Juan M.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.08.2024; Springer Nature B.V
• Subjects: Antigens; Autoimmune diseases; Biopsy; blood serum; class; Clinical medicine; cohort studies; Creatinine; Epidermal growth factor receptors; Glomerular filtration rate; histology; Kidney diseases; kidneys; Lupus; lupus erythematosus; Lupus nephritis; Medicine; Medicine & Public Health; Membranous nephropathy; nephritis; Nephropathy; Original Article; Prognosis; Renal failure; Rheumatology; Statistical analysis; Systemic lupus erythematosus; Exostosin; Erythematosus; Prognosis; Lupus nephritis; Membranous nephropathy; Systemic lupus

Introduction/Objectives The heterodimer exostosin-1/exostosin-2 (EXO-1/2) is a novel antigen observed in membranous nephropathy associated with systemic lupus erythematosus. This study aimed to evaluate the association between EXO-1/2 positivity in kidney biopsy and kidney outcomes. Methods The kidn...