Incidence of vulvar high-grade precancerous lesions and cancer in Denmark before and after introduction of HPV vaccination

• Published in: Gynecologic oncology Vol. 157; no. 3; pp. 664 - 670
• Main Authors: Rasmussen, Christina Louise, Thomsen, Louise T., Aalborg, Gitte Lerche, Kjaer, Susanne K.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2020
• Subjects: Adult; Aged; Aged, 80 and over; Denmark; Female; Human papillomavirus; Humans; Incidence; Middle Aged; Papillomavirus Infections - epidemiology; Papillomavirus Vaccines - pharmacology; Papillomavirus Vaccines - therapeutic use; Squamous cell carcinoma; Vulvar cancer; Vulvar high-grade squamous intraepithelial lesion; Vulvar Neoplasms - epidemiology; Denmark; Squamous cell carcinoma; CI; AAPC; HPV; HSIL; Incidence; uVIN; Human papillomavirus; VSCC; dVIN; Vulvar cancer; Vulvar high-grade squamous intraepithelial lesion; VIN

To assess the incidence of vulvar high-grade precancerous lesions and cancer in Denmark during 1997–2018. We identified incident vulvar cancer cases in the Danish Cancer Registry and incident cases of vulvar precancerous lesions in the Danish Pathology Register. We calculated age-standardized incide...