Colorectal cancer and trace elements alteration

• Published in: Journal of trace elements in medicine and biology Vol. 59; p. 126451
• Main Authors: Juloski, Jovan T., Rakic, Aleksandar, Ćuk, Vladica V., Ćuk, Vladimir M., Stefanović, Srđan, Nikolić, Dragica, Janković, Saša, Trbovich, Alexander M., De Luka, Silvio R.
• Format: Journal Article
• Language: English
• Published: Germany Elsevier GmbH 01.05.2020
• Subjects: Aged; Colon - chemistry; Colon - metabolism; Colorectal cancer; Colorectal Neoplasms - chemistry; Colorectal Neoplasms - metabolism; Cu/Zn ratio; Female; Healthy tissue; Humans; Male; Mass Spectrometry; Middle Aged; Quality Assurance, Health Care; Trace elements; Trace Elements - analysis; Trace elements; Cu/Zn ratio; Colorectal cancer; Healthy tissue

•Significant alterations of Na, K, Mg, Ca, Cu, Zn, Se, Mn, Cd, Cr and Hg in malignant tissue of CRC compared to adjacent healthy bowel tissue were found.•Cu/Zn ratio was significantly higher in CRC tissue and in patients with higher CRC stages.•Male subjects with CRC had significantly higher Ca2+ ti...