Advances in bio-nylon 5X: discovery of new lysine decarboxylases for the high-level production of cadaverine

• Published in: Green chemistry : an international journal and green chemistry resource : GC Vol. 22; no. 24; pp. 8656 - 8668
• Main Authors: Xue, Yaju, Zhao, Yongliang, Ji, Xiuling, Yao, Jiahao, Busk, Peter Kamp, Lange, Lene, Huang, Yuhong, Zhang, Suojiang
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 21.12.2020
• Subjects: Biocatalysts; Bioconversion; Cadaverine; E coli; Enzymes; Fibers; Green chemistry; Incubation; Lysates; Lysine; Lysine decarboxylase; Nylon; Pattern recognition; pH effects; Polymers; Thermal stability

Cadaverine (1,5-pentanediamine) is the most important precursor for nylon PA5X, which has an extremely competitive market due to the high consumption of engineered plastics and fibers. The key enzyme lysine decarboxylase is in desperate need for industrial bio-based cadaverine production. In this st...