Metabolic engineering of Corynebacterium glutamicum for the production of glutaric acid, a C5 dicarboxylic acid platform chemical

• Published in: Metabolic engineering Vol. 51; pp. 99 - 109
• Main Authors: Kim, Hee Taek, Khang, Tae Uk, Baritugo, Kei-Anne, Hyun, Sung Min, Kang, Kyoung Hee, Jung, Sol Hee, Song, Bong Keun, Park, Kyungmoon, Oh, Min-Kyu, Kim, Gi Bae, Kim, Hyun Uk, Lee, Sang Yup, Park, Si Jae, Joo, Jeong Chan
• Format: Journal Article
• Language: English
• Published: Belgium Elsevier Inc 01.01.2019
• Subjects: Codon optimization; Corynebacterium glutamicum; davTDBA; Fed-batch fermentation; Glutaric acid; His6-tag; L‐Lysine; davTDBA; Glutaric acid; Corynebacterium glutamicum; Fed-batch fermentation; L‐Lysine; His6-tag; Codon optimization; His-tag

Corynebacterium glutamicum was metabolically engineered for the production of glutaric acid, a C5 dicarboxylic acid that can be used as platform building block chemical for nylons and plasticizers. C. glutamicum gabT and gabD genes and Pseudomonas putida davT and davD genes encoding 5-aminovalerate...