A rare encounter with two cases of Budd‑Chiari syndrome in the Emergency Department: A case report

Budd-Chiari syndrome (BCS) is a rare disorder clinically characterized by abdominal pain, hepatomegaly and ascites. The condition is often related to thrombosis of the hepatic veins or the terminal portion of the inferior vena cava. A myeloproliferative disorder is the most identified underlying pro...

Full description

Saved in:
Bibliographic Details
Published inExperimental and therapeutic medicine Vol. 24; no. 6
Main Authors Stanciugelu, Alexandra, Petrica, Alina, Chiriac, Sorin Dan, Iurciuc, Mircea, Boruga, madalina Veronica, Balica, Nicolae, Mederle, Ovidiu Alexandru
Format Journal Article
LanguageEnglish
Published Athens Spandidos Publications 01.12.2022
Spandidos Publications UK Ltd
D.A. Spandidos
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Budd-Chiari syndrome (BCS) is a rare disorder clinically characterized by abdominal pain, hepatomegaly and ascites. The condition is often related to thrombosis of the hepatic veins or the terminal portion of the inferior vena cava. A myeloproliferative disorder is the most identified underlying prothrombotic risk factor, although almost one-half of affected patients are now recognized as having multiple underlying prothrombotic risk factors. Doppler ultrasound may be enough to confirm the diagnosis of BCS; however, computed tomography or magnetic resonance imaging is often employed. Anticoagulant therapy is the cornerstone of BCS treatment, but most patients also need additional treatment strategies. Most patients with BCS are now treated by endovascular intervention, which has improved survival rate in those afflicted by this disease. The long-term course of the disease can be complicated by progression or recurrence of the underlying myeloproliferative disorder. The present study reports the cases of two patients with BCS with the aim of alerting healthcare workers in Emergency Departments of this less common diagnosis in patients presenting with frequent complaints of abdominal pain.
AbstractList Budd-Chiari syndrome (BCS) is a rare disorder clinically characterized by abdominal pain, hepatomegaly and ascites. The condition is often related to thrombosis of the hepatic veins or the terminal portion of the inferior vena cava. A myeloproliferative disorder is the most identified underlying prothrombotic risk factor, although almost one-half of affected patients are now recognized as having multiple underlying prothrombotic risk factors. Doppler ultrasound may be enough to confirm the diagnosis of BCS; however, computed tomography or magnetic resonance imaging is often employed. Anticoagulant therapy is the cornerstone of BCS treatment, but most patients also need additional treatment strategies. Most patients with BCS are now treated by endovascular intervention, which has improved survival rate in those afflicted by this disease. The long-term course of the disease can be complicated by progression or recurrence of the underlying myeloproliferative disorder. The present study reports the cases of two patients with BCS with the aim of alerting healthcare workers in Emergency Departments of this less common diagnosis in patients presenting with frequent complaints of abdominal pain. Key words: Budd-Chiari syndrome, neoplastic disease, hepatomegaly, hepatic failure, thrombosis, endovascular intervention
Budd-Chiari syndrome (BCS) is a rare disorder clinically characterized by abdominal pain, hepatomegaly and ascites. The condition is often related to thrombosis of the hepatic veins or the terminal portion of the inferior vena cava. A myeloproliferative disorder is the most identified underlying prothrombotic risk factor, although almost one-half of affected patients are now recognized as having multiple underlying prothrombotic risk factors. Doppler ultrasound may be enough to confirm the diagnosis of BCS; however, computed tomography or magnetic resonance imaging is often employed. Anticoagulant therapy is the cornerstone of BCS treatment, but most patients also need additional treatment strategies. Most patients with BCS are now treated by endovascular intervention, which has improved survival rate in those afflicted by this disease. The long-term course of the disease can be complicated by progression or recurrence of the underlying myeloproliferative disorder. The present study reports the cases of two patients with BCS with the aim of alerting healthcare workers in Emergency Departments of this less common diagnosis in patients presenting with frequent complaints of abdominal pain.
ArticleNumber 730
Audience Academic
Author Chiriac, Sorin Dan
Mederle, Ovidiu Alexandru
Stanciugelu, Alexandra
Petrica, Alina
Iurciuc, Mircea
Boruga, madalina Veronica
Balica, Nicolae
AuthorAffiliation 3 Department of Emergency, ‘Pius Brînzeu’ Emergency Clinical County Hospital, 300736 Timisoara, Romania
5 Department of Ophthalmology, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
4 Department of Cardiology, Faculty of Medicine, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
7 Department of Surgery, Faculty of Medicine, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
2 Department of Emergency, Emergency Clinical Municipal Hospital, 300079 Timisoara, Romania
6 Department of Ear, Nose and Throat, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
1 Department of Surgery, Faculty of Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
AuthorAffiliation_xml – name: 4 Department of Cardiology, Faculty of Medicine, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
– name: 6 Department of Ear, Nose and Throat, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
– name: 7 Department of Surgery, Faculty of Medicine, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
– name: 3 Department of Emergency, ‘Pius Brînzeu’ Emergency Clinical County Hospital, 300736 Timisoara, Romania
– name: 2 Department of Emergency, Emergency Clinical Municipal Hospital, 300079 Timisoara, Romania
– name: 5 Department of Ophthalmology, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
– name: 1 Department of Surgery, Faculty of Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, 300041 Timisoara, Romania
Author_xml – sequence: 1
  fullname: Stanciugelu, Alexandra
– sequence: 2
  fullname: Petrica, Alina
– sequence: 3
  fullname: Chiriac, Sorin Dan
– sequence: 4
  fullname: Iurciuc, Mircea
– sequence: 5
  fullname: Boruga, madalina Veronica
– sequence: 6
  fullname: Balica, Nicolae
– sequence: 7
  fullname: Mederle, Ovidiu Alexandru
BookMark eNptkctOAyEYhYnRxOvWNYnrVmCGGXBhUus1MXGja0KZf1pMByowmu58BV_RJxFrYzQpLPgD55yc8O2jbecdIHRMybAQkp1C6oaMMDaktKqqLbRHa8kGlFC-vZ6JFHQXHcX4TPLiFRWC76FmhIMOgMEZ37sEAb_ZNMPpzWOjI0TsW3zRN83n-8d4ZnWwOC5dE3wH2DqcZoCvOgjTbF_iS1jokDpw6QyPVnYcYOFDOkQ7rZ5HOFqfB-jp-upxfDu4f7i5G4_uB6bgMg0m7SQPZal1xZiYaKgJEZo0suSiAdYKU1eUcVNSAboESTmnsgWpC11TyWRxgM5_chf9pIPG5CZBz9Ui2E6HpfLaqv8vzs7U1L8qWRVl_o4ccLIOCP6lh5jUs--Dy50Vq7mQnBP-RzXVc1DWtT6Hmc5Go0Z1UVZEkJJk1XCDKu8GOmsyvdbm-00GE3yMAdrf4pSob8gqQ1bfkNUKcvEF-1WcXQ
CitedBy_id crossref_primary_10_1186_s43055_024_01305_z
ContentType Journal Article
Copyright COPYRIGHT 2022 Spandidos Publications
Copyright Spandidos Publications UK Ltd. 2022
Copyright: © Stanciugelu et al. 2020
Copyright_xml – notice: COPYRIGHT 2022 Spandidos Publications
– notice: Copyright Spandidos Publications UK Ltd. 2022
– notice: Copyright: © Stanciugelu et al. 2020
DBID AAYXX
CITATION
3V.
7RV
7X7
7XB
8FI
8FJ
8FK
ABUWG
AFKRA
AN0
BENPR
CCPQU
FYUFA
GHDGH
K9.
KB0
M0S
NAPCQ
PQEST
PQQKQ
PQUKI
PRINS
5PM
DOI 10.3892/etm.2022.11666
DatabaseName CrossRef
ProQuest Central (Corporate)
ProQuest Nursing and Allied Health Journals
ProQuest - Health & Medical Complete保健、医学与药学数据库
ProQuest Central (purchase pre-March 2016)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central
British Nursing Database
AUTh Library subscriptions: ProQuest Central
ProQuest One Community College
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Health & Medical Complete (Alumni)
Nursing & Allied Health Database (Alumni Edition)
Health & Medical Collection (Alumni Edition)
Nursing & Allied Health Premium
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
PubMed Central (Full Participant titles)
DatabaseTitle CrossRef
ProQuest One Academic Eastern Edition
ProQuest Health & Medical Complete (Alumni)
British Nursing Index with Full Text
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest Nursing & Allied Health Source
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Central China
ProQuest Hospital Collection (Alumni)
ProQuest Central
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
Health Research Premium Collection
ProQuest One Academic UKI Edition
Health and Medicine Complete (Alumni Edition)
ProQuest Nursing & Allied Health Source (Alumni)
ProQuest One Academic
ProQuest Central (Alumni)
DatabaseTitleList
ProQuest One Academic Eastern Edition


Database_xml – sequence: 1
  dbid: 7X7
  name: ProQuest - Health & Medical Complete保健、医学与药学数据库
  url: https://search.proquest.com/healthcomplete
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Pharmacy, Therapeutics, & Pharmacology
EISSN 1792-1015
ExternalDocumentID A734608040
10_3892_etm_2022_11666
GeographicLocations Romania
China
GeographicLocations_xml – name: Romania
– name: China
GroupedDBID ---
0R~
3V.
53G
7RV
7X7
8FI
8FJ
AAKDD
AAYXX
ABDBF
ABJNI
ABUWG
ACGFS
ADBBV
AENEX
AFKRA
AHMBA
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AN0
BENPR
BKEYQ
BNQBC
BPHCQ
BVXVI
C45
CCPQU
CITATION
EBD
EBS
EJD
ESX
F5P
FYUFA
H13
HMCUK
HUR
HZ~
IAO
IHR
IPNFZ
ITC
NAPCQ
O9-
OK1
OVD
PQQKQ
PROAC
RIG
RPM
TEORI
UKHRP
7XB
8FK
K9.
PQEST
PQUKI
PRINS
5PM
ID FETCH-LOGICAL-c359t-bfbc3544aa6228bae7008a0d9458de2f8c76125c418ea4e915519fe9a3a719293
IEDL.DBID RPM
ISSN 1792-0981
IngestDate Tue Sep 17 21:30:46 EDT 2024
Thu Oct 10 16:11:30 EDT 2024
Thu Feb 22 23:41:21 EST 2024
Fri Feb 02 04:16:59 EST 2024
Fri Aug 23 03:06:34 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed false
IsScholarly true
Issue 6
Language English
License This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c359t-bfbc3544aa6228bae7008a0d9458de2f8c76125c418ea4e915519fe9a3a719293
Notes Dr Mircea Iurciuc, Department of Cardiology, Faculty of Medicine, Multidisciplinary Center for Research, Evaluation, Diagnosis and Therapies in Oral Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, Piata Eftimie Murgu 2, 300041 Timisoara, Romania iurciuc.mircea@umft.ro
Contributed equally
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9634885/
PQID 2758955055
PQPubID 2044959
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_9634885
proquest_journals_2758955055
gale_infotracmisc_A734608040
gale_infotracacademiconefile_A734608040
crossref_primary_10_3892_etm_2022_11666
PublicationCentury 2000
PublicationDate 2022-12-01
PublicationDateYYYYMMDD 2022-12-01
PublicationDate_xml – month: 12
  year: 2022
  text: 2022-12-01
  day: 01
PublicationDecade 2020
PublicationPlace Athens
PublicationPlace_xml – name: Athens
PublicationTitle Experimental and therapeutic medicine
PublicationYear 2022
Publisher Spandidos Publications
Spandidos Publications UK Ltd
D.A. Spandidos
Publisher_xml – name: Spandidos Publications
– name: Spandidos Publications UK Ltd
– name: D.A. Spandidos
SSID ssj0000561885
Score 2.328515
Snippet Budd-Chiari syndrome (BCS) is a rare disorder clinically characterized by abdominal pain, hepatomegaly and ascites. The condition is often related to...
SourceID pubmedcentral
proquest
gale
crossref
SourceType Open Access Repository
Aggregation Database
SubjectTerms Abdomen
Anticoagulants
Ascites
Care and treatment
Case Report
Case reports
Case studies
Diagnosis
Edema
Emergency medical care
Hepatic vein thrombosis
Hypertension
Liver
Medical imaging
Medical prognosis
Mutation
Pain
Patients
Thrombosis
Ultrasonic imaging
Veins & arteries
SummonAdditionalLinks – databaseName: AUTh Library subscriptions: ProQuest Central
  dbid: BENPR
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3NTuMwELagXPaCYNnVdhfQHBBciEgdO7G5oLZbhJBAFQKJmxU7juglBZoKceMVeEWehJn8UMqBmyXn12PPfB7PfMPYXqyd1U6IQDutArTQGvVglmPLojmQumcjSnC-uIzPbsT5rbxtHG6zJqyy1YmVos6mjnzkRxyBrSY4LU_uHwKqGkWnq00JjVW2xom5qcPWBqPL8dWHl4XwsarqcuLE40GoVa9mbkQ7zY98SbnonKPeiCuaxIVl-qqfv8ZMfjJCpxtsvUGP0K_FvclWfPGT7Y9r-unnQ7heZFPNDmEfxgti6uctlvUBt8YeiLtyTgMK5IWF8mkKDo3ZDKY5DOZZ9vbyOryb4CYaWj4DmBSASBFGbbIm_Ecz9lhFqB9Dv7od6uOHX-zmdHQ9PAuaKguBi6QuA5tbbAiRpjHnyqY-QViQhpkWUmWe58olhIKc6CmfCk988j2de51GaYLwUEe_WaeYFv4PAxklRGCnpFWhSCyd6IY-Fko6jTgos1120I6wua_JNAxuQkgWBmVhSBamkgVeSQIwtMpwuF3aJAvge4ivyvSTSMQIdkXYZdtLV-LqcMvdrQhNszpnZjGXuixZEuvHZxHr9nJPMbmr2LdRY6HSk3-_f_A_9oP-pg582Wad8nHudxC-lHa3maPve5Dviw
  priority: 102
  providerName: ProQuest
Title A rare encounter with two cases of Budd‑Chiari syndrome in the Emergency Department: A case report
URI https://www.proquest.com/docview/2758955055
https://pubmed.ncbi.nlm.nih.gov/PMC9634885
Volume 24
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3NThsxELaAXnqp-qumpdEcKnphyf7Ya7u3kAahSqCoAik3a-31ikiwQWSjihuvwCv2STrj3W0Ix94s2dZ6PWPPN_bMZ8a-5tpZ7TiPtNMqQgutcR8sKyxZNAdCJzajBOez8_z0kv-ci_kOE30uTAjad3ZxVF_fHNWLqxBbeXvjRn2c2Gh2NkGlQb0To122K7PsiYveEnrniQpPcaKupVGsVdKSNaJpTke-ofTzNMWtIg_MiBtj9HxLfh4m-cTunLxmrzrACON2YG_Yjq_fsoNZyzh9fwgXmwSq1SEcwGzDRX3_jpVjQG_YA9FVrmkOgQ5eofm9BIf2awXLCo7XZfnn4XFytUC_GXoKA1jUgOAQpn1-JvxAy3UXgtK_wzh0h_bG4T27PJleTE6j7mGFyGVCN5GtLBY4L4o8TZUtvEQkUMSl5kKVPq2UkwR8HE-UL7gnCvlEV14XWSEREersA9url7X_yEBkkjjrlLAq5tLSJW7sc66E0wh9Sjtg3_oZNrctf4ZBv4NkYVAWhmRhgiywJQnA0MLC6XZFlx-A3yGKKjOWGc8R3_J4wPa3WuKCcNvVvQhNtyBXJkW_SJM3JgZMbon137CIaHu7BvUvEG53-vbpv3t-Zi_pR9swmH2219yt_RcEM40dogrP5ZC9OJ6ez34Ngyr_Bb2A9_E
link.rule.ids 230,315,733,786,790,891,12077,21409,27946,27947,31743,33768,43334,43829,53816,53818,74091,74648
linkProvider National Library of Medicine
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LTxsxELYKPcClKi1V09J2DggurNis7bXNpUp5KKWAOAQpN2vt9YpcNkA2qrjxF_iL_SXM7IMQDr1Z8j499szn8cw3jG2nxjvjhYiMNzpCC21QD-YFthyaA2n6jlOC8_lFOrwSp2M5bh1uszasstOJtaLOp5585PsJAltDcFr-vLmNqGoUna62JTRW2FvBOSfufDVWzz4WQse6rsqJ0y6JYqP7DW8jWulkP1SUiZ4kqDXSmiRxYZdea-fXEZMvTNDJe_auxY4waIS9wd6E8gPbuWzIp-_3YLTIpZrtwQ5cLmip7z-yfAC4MQ5AzJVzGk4gHyxUf6fg0ZTNYFrAr3me_3t4PLye4BYaOjYDmJSAOBGOu1RNOEIjdlfHpx_AoL4dmsOHTXZ1cjw6HEZtjYXIc2mqyBUOG0JkWZok2mVBISjI4twIqfOQFNorwkBe9HXIRCA2-b4pgsl4phAcGv6JrZbTMnxmILki-jotnY6FcnSeG4dUaOkNoqDc9dhuN8L2pqHSsLgFIVlYlIUlWdhaFnglCcDSGsPh9lmbKoDvIbYqO1BcpAh1RdxjW0tX4trwy92dCG27Nmd2MZN6TC2J9fmziHN7uaecXNfc26ivUOXJL_9_8A-2Nhydn9mz3xd_vrJ1-rMmBGaLrVZ38_ANgUzlvtez9QnKk_EQ
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LTxsxELYKlRCXCgqIUErnUMGFVTa79trupUqBiPJSDiDlZq29XiWXDZCNKm79C_xFfgkz-yANh94seZ8ez8xne-Ybxr4n2lntOA-00ypAD63RDmY5tiy6A6F7NqYE5-ub5PyOX4zEqIl_mjVhla1NrAx1NnW0R96NENhqgtOimzdhEcPTwc_7h4AqSNFJa1NOY4V9lLhoISWVI_m230JIWVUVOnEKRkGoVa_mcESPHXV9SVnpUYQWJKkIExc-6r2lfh89-Y87GmywTw2OhH4t-E32wRef2eGwJqJ-OobbRV7V7BgOYbigqH7aYlkfcJHsgVgs5zS0QPuxUP6ZgkO3NoNpDr_mWfby9_lkPMHlNLTMBjApADEjnLVpm3CKDu2xilX_Af3qdqgPIrbZ3eDs9uQ8aOotBC4WugxsbrHBeZomUaRs6iUChDTMNBcq81GunCQ85HhP-ZR7Ypbv6dzrNE4lAkUd77DVYlr4XQYilkRlp4RVIZeWznZDn3AlnEZElNkOO2pH2NzXtBoGlyMkC4OyMCQLU8kCryQBGNI3HG6XNmkD-B5irjJ9GfMEYS8PO2x_6UrUE7fc3YrQNHo6M4tZ1WFySaxvn0X828s9xWRc8XCj7ULzJ_b-_-BvbA0nqrn6fXP5ha3Tj9XRMPtstXyc-6-IaUp7UE3WVwcL9UU
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+rare+encounter+with+two+cases+of+Budd-Chiari+syndrome+in+the+Emergency+Department%3A+A+case+report&rft.jtitle=Experimental+and+therapeutic+medicine&rft.au=Stanciugelu%2C+Alexandra&rft.au=Petrica%2C+Alina&rft.au=Chiriac%2C+Sorin+Dan&rft.au=Iurciuc%2C+Mircea&rft.date=2022-12-01&rft.pub=Spandidos+Publications&rft.issn=1792-0981&rft.volume=24&rft.issue=6&rft_id=info:doi/10.3892%2Fetm.2022.11666&rft.externalDocID=A734608040
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1792-0981&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1792-0981&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1792-0981&client=summon