A rare encounter with two cases of Budd‑Chiari syndrome in the Emergency Department: A case report

• Published in: Experimental and therapeutic medicine Vol. 24; no. 6
• Main Authors: Stanciugelu, Alexandra, Petrica, Alina, Chiriac, Sorin Dan, Iurciuc, Mircea, Boruga, madalina Veronica, Balica, Nicolae, Mederle, Ovidiu Alexandru
• Format: Journal Article
• Language: English
• Published: Athens Spandidos Publications 01.12.2022; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Abdomen; Anticoagulants; Ascites; Care and treatment; Case Report; Case reports; Case studies; Diagnosis; Edema; Emergency medical care; Hepatic vein thrombosis; Hypertension; Liver; Medical imaging; Medical prognosis; Mutation; Pain; Patients; Thrombosis; Ultrasonic imaging; Veins & arteries; Romania; China
• DOI: 10.3892/etm.2022.11666
• ISSN: 1792-0981

Budd-Chiari syndrome (BCS) is a rare disorder clinically characterized by abdominal pain, hepatomegaly and ascites. The condition is often related to thrombosis of the hepatic veins or the terminal portion of the inferior vena cava. A myeloproliferative disorder is the most identified underlying prothrombotic risk factor, although almost one-half of affected patients are now recognized as having multiple underlying prothrombotic risk factors. Doppler ultrasound may be enough to confirm the diagnosis of BCS; however, computed tomography or magnetic resonance imaging is often employed. Anticoagulant therapy is the cornerstone of BCS treatment, but most patients also need additional treatment strategies. Most patients with BCS are now treated by endovascular intervention, which has improved survival rate in those afflicted by this disease. The long-term course of the disease can be complicated by progression or recurrence of the underlying myeloproliferative disorder. The present study reports the cases of two patients with BCS with the aim of alerting healthcare workers in Emergency Departments of this less common diagnosis in patients presenting with frequent complaints of abdominal pain.