Trait- and Frequency-Dependent Dysfunctional Habituation to Trigeminal Nociceptive Stimulation in Trigeminal Autonomic Cephalalgias

• Published in: The journal of pain Vol. 19; no. 9; pp. 1040 - 1048
• Main Authors: Perrotta, Armando, Coppola, Gianluca, Anastasio, Maria Grazia, De Icco, Roberto, Ambrosini, Anna, Serrao, Mariano, Parisi, Vincenzo, Evangelista, Maurizio, Sandrini, Giorgio, Pierelli, Francesco
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2018
• Subjects: Cluster headache; habituation; nociceptive blink reflex; paroxysmal hemicrania; Cluster headache; paroxysmal hemicrania; habituation; nociceptive blink reflex; cluster headache

•Trigeminal autonomic cephalalgias (TACs) shared a deficit of habituation to pain.•TACs habituation loss to pain was detectable only at faster stimulation frequencies.•In TACs shared pathogenetic factors were in parallel with common clinical features. We investigated whether the stimulation frequenc...