Brain tumor classification from multi-modality MRI using wavelets and machine learning

• Published in: Pattern analysis and applications : PAA Vol. 20; no. 3; pp. 871 - 881
• Main Authors: Usman, Khalid, Rajpoot, Kashif
• Format: Journal Article
• Language: English
• Published: London Springer London 01.08.2017; Springer Nature B.V
• Subjects: Brain; Brain cancer; Classification; Computer Science; Edema; Feature extraction; Image contrast; Image segmentation; Machine learning; Magnetic resonance imaging; NMR; Nuclear magnetic resonance; Pattern Recognition; Short Paper; Skull; Wavelet analysis; Brain tumor; Random forest; Wavelet transform; Segmentation; MRI; Multi-modality
• ISSN: 1433-7541; 1433-755X
• DOI: 10.1007/s10044-017-0597-8

In this paper, we propose a brain tumor segmentation and classification method for multi-modality magnetic resonance imaging scans. The data from multi-modal brain tumor segmentation challenge (MICCAI BraTS 2013) are utilized which are co-registered and skull-stripped, and the histogram matching is performed with a reference volume of high contrast. From the preprocessed images, the following features are then extracted: intensity, intensity differences, local neighborhood and wavelet texture. The integrated features are subsequently provided to the random forest classifier to predict five classes: background, necrosis, edema, enhancing tumor and non-enhancing tumor, and then these class labels are used to hierarchically compute three different regions ( complete tumor, active tumor and enhancing tumor ). We performed a leave-one-out cross-validation and achieved 88% Dice overlap for the complete tumor region, 75% for the core tumor region and 95% for enhancing tumor region, which is higher than the Dice overlap reported from MICCAI BraTS challenge.