Evidence for a white matter lesion size threshold to support the diagnosis of relapsing remitting multiple sclerosis

• Published in: Multiple sclerosis and related disorders Vol. 29; pp. 124 - 129
• Main Authors: Grahl, S., Pongratz, V., Schmidt, P., Engl, C., Bussas, M., Radetz, A., Gonzalez-Escamilla, G., Groppa, S., Zipp, F., Lukas, C., Kirschke, J., Zimmer, C., Hoshi, M., Berthele, A., Hemmer, B., Mühlau, M.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.04.2019
• Subjects: Relapsing-remitting multiple sclerosis; Structural MRI; White matter lesion; White matter lesion size threshold; CS1; TIV; CS2; D; MS1; MS2; White matter lesion; LOESS; sWML; WM; CSF; T2w; OR; GM; MS; ROC; Structural MRI; CIS; CS; TE; White matter lesion size threshold; TI; WML; Relapsing-remitting multiple sclerosis; T1w; TR

•White matter lesions smaller than 3 mm are more frequent in patients with multiple sclerosis than in control subjects.•White matter lesion size threshold of 3 mm distinguishes best between MS patients and control subjects.•Consistent findings across two 3 T scanners from different vendors. The numb...