Label-free profiling of cell dynamics: A sequence of impedance-based assays to estimate tumor cell invasiveness in vitro

• Published in: Experimental cell research Vol. 359; no. 1; pp. 243 - 250
• Main Authors: Láng, Orsolya, Kőhidai, László, Wegener, Joachim
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2017
• Subjects: Biological Assay - methods; Cell adhesion; Cell Line, Tumor; Cell migration; Cell Movement; ECIS; Electric cell-substrate impedance sensing; Electric Impedance; Humans; Kinetics; Metastatic potential; Micromotion; Neoplasm Invasiveness - pathology; Staining and Labeling; Wound Healing; Wound healing; Micromotion; Cell adhesion; Electric cell-substrate impedance sensing; ECIS; Metastatic potential; Cell migration

Dynamic properties of cancer cells, most notably their ability to migrate, have been correlated successfully with their invasive nature in vivo. To establish a stronger experimental basis for such a correlation we subjected five different cancer cell lines of well-defined metastatic potential to a s...