Characterization of brain functional connectivity in treatment-resistant depression

• Published in: Progress in neuro-psychopharmacology & biological psychiatry Vol. 111; p. 110346
• Main Authors: Amiri, Saba, Arbabi, Mohammad, Kazemi, Kamran, Parvaresh-Rizi, Mansour, Mirbagheri, Mehdi M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 20.12.2021
• Subjects: Adult; Brain - physiopathology; Brain - surgery; Brain stimulation; Deep Brain Stimulation; Depression; Depressive Disorder, Treatment-Resistant - physiopathology; Depressive Disorder, Treatment-Resistant - surgery; Female; Functional Laterality; Gyrus Cinguli - physiopathology; Habenula - physiopathology; Humans; Magnetic Resonance Imaging; Male; Nucleus Accumbens - physiopathology; Resting-state fMRI; Sex Factors; Thalamus - physiopathology; Treatment; Resting-state fMRI; Depression; Treatment; Brain stimulation

To characterize the functional connectivity (FC) of target brain regions for deep brain stimulation (DBS) in patients with treatment-resistant depression (TRD), and to evaluate its gender and brain lateralization dependence. Thirty-one TRD patients and twenty-nine healthy control (HC) subjects parti...