Biomonitoring of humans exposed to arsenic, chromium, nickel, vanadium, and complex mixtures of metals by using the micronucleus test in lymphocytes

• Published in: Mutation research Vol. 770; no. Pt A; pp. 140 - 161
• Main Authors: Annangi, Balasubramanyam, Bonassi, Stefano, Marcos, Ricard, Hernández, Alba
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2016
• Subjects: Biomonitoring; Environmental Exposure; Environmental Monitoring - methods; Humans; Lymphocytes - drug effects; Lymphocytes - ultrastructure; Metals; Metals - toxicity; Micronucleus; Micronucleus Tests - methods; Peripheral blood lymphocytes; Biomonitoring; Peripheral blood lymphocytes; Metals; Micronucleus

Various metals have demonstrated genotoxic and carcinogenic potential via different mechanisms. Until now, biomonitoring and epidemiological studies have been carried out to assess the genotoxic risk to exposed human populations. In this sense, the use of the micronucleus assay in peripheral blood l...