An emerging and expanding clade accounts for the persistent outbreak of Coxsackievirus A6-associated hand, foot, and mouth disease in China since 2013

• Published in: Virology (New York, N.Y.) Vol. 518; pp. 328 - 334
• Main Authors: He, Shuizhen, Chen, Mengyuan, Wu, Wenhui, Yan, Qiang, Zhuo, Zhihao, Su, Xiaosong, Zhang, Shiyin, Ge, Shengxiang, Xia, Ningshao
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2018
• Subjects: Coxsackievirus A6 (CV-A6); Epidemic; Evolution analysis; Hand, foot, and mouth disease (HFMD); Human enteroviruses (human EVs); Epidemic; Human enteroviruses (human EVs); Hand, foot, and mouth disease (HFMD); Evolution analysis; Coxsackievirus A6 (CV-A6)

Enterovirus (EV)-A71 and Coxsackievirus (CV)-A16 have historically been the major pathogens of hand, foot, and mouth disease (HMFD) in China; however, CV-A6， which had previously received little attention, became the predominant pathogen in 2013, and has remained one of the common pathogens since th...