Noncovalent conformational lock-based molecular engineering improves NIR-II photoacoustic/photothermal performance of semiconducting polymer nanoparticles for efficient phototheranostics

• Published in: Science China materials Vol. 66; no. 12; pp. 4865 - 4874
• Main Authors: Chen, Yang, Yang, Guangzhao, Li, Ping, Yin, Likun, Chen, Lu, Liu, Yu, Liang, Xin, Chen, Ying, Yin, Chao, Fan, Quli
• Format: Journal Article
• Language: English
• Published: Beijing Science China Press 01.12.2023; Springer Nature B.V
• Subjects: Ablation; Biocompatibility; Chemistry and Materials Science; Chemistry/Food Science; Materials Science; Nanoparticles; Near infrared radiation; Polymers; Tumors; noncovalent conformational lock; semiconducting polymer nanoparticles; photoacoustic imaging; photothermal therapy; near-infrared-II window

The development of near-infrared-II (NIR-II)-absorbing nano-agents for NIR-II photoacoustic imaging (PAI)-guided photothermal therapy (PTT) provides opportunities to advance the development of deep tissue photo-theranostics. Despite the superiority of semiconducting polymer nanoparticles (SPNs) for...