Attenuation of A(H7N9) influenza virus infection in mice exposed to cigarette smoke

• Published in: Npj viruses Vol. 2; no. 1; pp. 16 - 8
• Main Authors: Fukuyama, Satoshi, Shoemaker, Jason E., Zhao, Dongming, Nagajima, Noriko, Tomita, Yuriko, Maemura, Tadashi, da Silva Lopes, Tiago Jose, Watanabe, Tokiko, Yamayoshi, Seiya, Hasegawa, Hideki, Kawaoka, Yoshihiro
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 25.03.2024; Nature Publishing Group UK; Nature Portfolio
• Subjects: Antigens; Avian flu; Body weight loss; Bronchitis; Cell cycle; Chemokines; Cigarette smoke; Cytokines; Emphysema; Epidemics; Follicles; Immune response; Immunohistochemistry; Immunoregulation; Infections; Influenza A; Lung cancer; Lung diseases; Lungs; Pathogenicity; Pathology; Poultry; Viral infections; Viruses; China

Influenza A(H7N9) virus showed high pathogenicity in humans when it emerged in 2013. Cigarette smoke (CS) causes pulmonary diseases including bronchitis, emphysema, and lung cancer. Although habitual smoking is thought to increase the risk of severe seasonal influenza virus infection, its effect on...