Comparison of 2-Chloroprocaine, Bupivacaine, and Lidocaine for Spinal Anesthesia in Patients Undergoing Knee Arthroscopy in an Outpatient Setting: A Double-Blind Randomized Controlled Trial

• Published in: Regional anesthesia and pain medicine Vol. 41; no. 5; pp. 576 - 583
• Main Authors: Teunkens, An, Vermeulen, Kristien, Van Gerven, Elke, Fieuws, Steffen, Van de Velde, Marc, Rex, Steffen
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group LTD 01.09.2016
• Subjects: Adult; Aged; Ambulatory Surgical Procedures - adverse effects; Ambulatory Surgical Procedures - methods; Anesthesia; Anesthesia, Spinal - adverse effects; Anesthesia, Spinal - methods; Anesthetics, Local - administration & dosage; Anesthetics, Local - adverse effects; Arthroscopy - adverse effects; Belgium; Bupivacaine - administration & dosage; Bupivacaine - adverse effects; Cardiac arrhythmia; Clinical trials; Double-Blind Method; Double-blind studies; Endoscopy; Female; Humans; Hypotension; Kaplan-Meier Estimate; Knee; Knee Joint - innervation; Knee Joint - surgery; Lidocaine - administration & dosage; Lidocaine - adverse effects; Male; Middle Aged; Motor Activity - drug effects; Patient satisfaction; Procaine - administration & dosage; Procaine - adverse effects; Procaine - analogs & derivatives; Prospective Studies; Recovery of Function; Regional anesthesia; Sensory Thresholds - drug effects; Time Factors; Treatment Outcome; Young Adult

Knee arthroscopy is a well-established procedure in day-case surgery, which is frequently performed under spinal anesthesia. It is, however, controversial whether the choice for a specific local anesthetic translates into relevant outcomes. We hypothesized that the use of 2-chloroprocaine would be a...