Opportunities for developing neural stem cell treatments for acute ischemic stroke: A systematic review and gap analysis

• Published in: Journal of clinical neuroscience Vol. 120; pp. 64 - 75
• Main Authors: Buchlak, Quinlan D, Esmaili, Nazanin, Moore, Justin
• Format: Journal Article
• Language: English
• Published: Scotland Elsevier Ltd 01.02.2024
• Subjects: Animals; Humans; Ischemic Stroke - therapy; Neural Stem Cells - transplantation; Stem Cell Transplantation - methods

•3,396 articles were screened and 33 met inclusion criteria.•Many studies appeared to be at risk of bias.•Most studies were preclinical and involved stem cell administration within 24 h.•Stem cell therapy appears to be associated with beneficial effects post stroke.•A gap analysis identified numerou...