A critical examination of the use of the Freundlich isotherm in characterizing molecularly imprinted polymers (MIPs)

• Published in: Analytica chimica acta Vol. 528; no. 1; pp. 107 - 113
• Main Authors: Rushton, Gregory T., Karns, Chelsey L., Shimizu, Ken D.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 03.01.2005; Elsevier
• Subjects: Adsorption isotherms; Analytical chemistry; Analytical methods; Chemistry; Chromatographic methods and physical methods associated with chromatography; Cinchonine; Exact sciences and technology; Freundlich isotherm; Molecular imprinting; Other chromatographic methods; Polymers; Spectrometric and optical methods; Cinchonine; Analytical methods; Adsorption isotherms; Polymers; Molecular imprinting; Freundlich isotherm; Chemical analysis; Molecular structure; Adsorption isotherm; HPLC chromatography; Polymer; Modeling; Cinchonine: Analytical methods; Critical study; Ultraviolet visible spectrometry

The Freundlich isotherm (FI) has previously been shown to be useful in modeling the binding properties of non-covalent molecularly imprinted polymers (MIPs). The advantage of the FI is that it is a heterogeneous binding model that can accommodate and measure the heterogeneity inherent in MIPs. Howev...