The case for oxygen free radicals in the pathogenesis of ischemic acute renal failure

• Published in: Nephron (2015) Vol. 49; no. 1; p. 9
• Main Authors: Canavese, C, Stratta, P, Vercellone, A
• Format: Journal Article
• Language: English
• Published: Switzerland 1988
• Subjects: Acute Kidney Injury - etiology; Free Radicals - metabolism; Humans; Ischemia - complications; Kidney - blood supply; Oxygen Consumption

One of the more glaring paradoxes of ischemic acute renal failure is that such injury appears to be worse in the kidney as opposed to other organs, even though the kidney is the best oxygenated. An answer can be deduced from the anatomical and physiological background, together with a reappraisal of...