TNFα and Reactive Oxygen Signaling in Vascular Smooth Muscle Cells in Hypertension and Atherosclerosis

• Published in: American journal of hypertension Vol. 33; no. 10; pp. 902 - 913
• Main Authors: Lamb, Fred S, Choi, Hyehun, Miller, Michael R, Stark, Ryan J
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 21.10.2020
• Subjects: Compendium on Hypertension

Hypertension and atherosclerosis, the predecessors of stroke and myocardial infarction, are chronic vascular inflammatory reactions. Tumor necrosis factor alpha (TNFα), the “master” proinflammatory cytokine, contributes to both the initiation and maintenance of vascular inflammation. TNFα induces re...