Construction of a 13‐microRNA‐based signature and prognostic nomogram for predicting overall survival in patients with hepatocellular carcinoma

• Published in: Hepatology research Vol. 50; no. 10; pp. 1151 - 1163
• Main Authors: Zheng, Zhihua, Wen, Yi, Nie, Kechao, Tang, Shuting, Chen, Xu, Lan, Shaoyang, Pan, Jinglin, Jiang, Kailin, Jiang, Xiaotao, Liu, Peng, Yan, Yanhua, Liu, Fengbin, Liu, Yufeng, Li, Peiwu
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.10.2020
• Subjects: Genes; Genomes; Hepatocellular carcinoma; Liver cancer; Malignancy; Medical prognosis; Metastases; Metastasis; microRNA; MicroRNAs; miRNA; miRNA‐based risk signature; Ontology; overall survival; Prognosis; prognostic nomogram; Survival

Aim Hepatocellular carcinoma (HCC) is a common malignancy associated with a poor prognosis due to difficulties in reliably estimating overall survival (OS). MicroRNAs (miRNAs) play critical roles in HCC initiation, progression, and metastasis and are highly correlated with patient prognosis. Thus, m...