Interaction of the non-phosphorylated peptide G7-18NATE with Grb7-SH2 domain requires phosphate for enhanced affinity and specificity - Gunzburg, Menachem J.; Ambaye, Nigus D.; Del Borgo, Mark P.; Pero, Stephanie C.; Krag, David N.; Wilce, Matthew C.J.; Wilce, Jacqueline A. (Journal of molecular recognition, 2012)
Keywords: Adaptor Proteins, Signal Transducing - antagonists & inhibitors; Adaptor Proteins, Signal Transducing - chemistry; Amino Acid Sequence; Breast cancer; Breast Neoplasms - drug therapy; Cell Adhesion - drug effects; Cell Line, Tumor; Cell Movement - drug effects; Female; GRB10 Adaptor Protein - antagonists & inhibitors; GRB10 Adaptor Protein - chemistry; GRB2 Adaptor Protein - antagonists & inhibitors; GRB2 Adaptor Protein - chemistry; Grb7; GRB7 Adaptor Protein - antagonists & inhibitors; GRB7 Adaptor Protein - chemistry; Humans; Molecular Sequence Data; Non phosphorylated cyclic peptide; Peptide inhibitor; Peptides, Cyclic - chemistry; Peptides, Cyclic - pharmacology; Phosphates - chemistry; Phosphates - metabolism; Protein Binding; Sensitivity and Specificity; SH2 domain; src Homology Domains; Surface Plasmon resonance; Surface Plasmon Resonance - methods