Minimally invasive ethyl cellulose ethanol ablation in domesticated cats with naturally occurring head and neck cancers: Six cats

• Published in: Veterinary & comparative oncology Vol. 19; no. 3; pp. 492 - 500
• Main Authors: Lai, Yen‐Hao Erik, Morhard, Robert, Ramanujam, Nirmala, Nolan, Michael W.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.2021
• Subjects: Animals; blood serum; Carcinoma, Squamous Cell - drug therapy; Carcinoma, Squamous Cell - veterinary; Cat Diseases - drug therapy; Cats; Cellulose - analogs & derivatives; Cellulose - therapeutic use; Ethanol; ethyl cellulose; fever; head; head and neck cancer; Head and Neck Neoplasms - drug therapy; Head and Neck Neoplasms - veterinary; injection site; intratumoral injection; minimally invasive procedure; neck; neoplasm progression; pain; palliative; Pilot Projects; poisoning; Quality of Life; squamous cell carcinoma; surgical alternative; therapeutics; surgical alternative; minimally invasive procedure; head and neck cancer; palliative; intratumoral injection

It is difficult to retain tumoricidal doses of ethanol in large or unencapsulated tumours without causing intoxication or damaging surrounding tissue. Ethyl cellulose‐ethanol ablation (ECEA) overcomes this limitation by trapping ethanol intratumorally. To evaluate the safety of ECEA and to develop a...