Investigation of the identification point system adaptation in cocaine, benzoylecgonine and ecgonine methyl ester using a single quadrupole mass spectrometer

• Published in: Rapid communications in mass spectrometry Vol. 23; no. 23; pp. 3772 - 3780
• Main Authors: Pistos, C., Karampela, S., Papoutsis, I., Athanaselis, S., Spiliopoulou, Ch, Maravelias, C.
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 15.12.2009
• Subjects: Cocaine - analogs & derivatives; Cocaine - blood; Cocaine - chemistry; Drug Stability; European Union; Guidelines as Topic; Humans; Mass Spectrometry - methods; Reproducibility of Results; Sensitivity and Specificity

At present, no official criteria exist for drug identification using single quadrupole mass spectrometers although the European Union (EU) criteria for compound identification have been adopted. These criteria are evaluated with respect to the confirmation of cocaine and its metabolites by single qu...