Efficacy and long‐term durability of intradermal recombinant hepatitis B virus vaccine among intramuscular vaccine nonresponders: A prospective study in healthcare personnel

• Published in: Journal of gastroenterology and hepatology Vol. 30; no. 12; pp. 1782 - 1787
• Main Authors: Kalchiem‐Dekel, Or, Grupel, Daniel, Bouchnik, Lea, Sikuler, Emanuel, Ben‐Yakov, Gil
• Format: Journal Article
• Language: English
• Published: Australia 01.12.2015
• Subjects: Female; Health Personnel; healthcare personnel; Hepatitis B - prevention & control; Hepatitis B Antibodies - blood; Hepatitis B Surface Antigens - immunology; Hepatitis B Vaccines - administration & dosage; Hepatitis B Vaccines - immunology; Hepatitis B virus; Hepatitis B virus - immunology; Humans; Injections, Intramuscular; Injections, Subcutaneous; intradermal; intramuscular; Male; Middle Aged; Prospective Studies; Safety; Time Factors; vaccine; Vaccines, Synthetic - administration & dosage; Vaccines, Synthetic - immunology; viral hepatitis B; healthcare personnel; intramuscular; vaccine; viral hepatitis B; intradermal

Background: Data on efficacy, safety, and durability of intradermal vaccine administration in persons who have not responded appropriately to intramuscular administration of hepatitis B virus (HBV) vaccine are relatively scarce. Methods: We designed a prospective case series in an urban tertiary car...