Construction and Validation of a New Model for the Prediction of Rupture in Patients with Intracranial Aneurysms

• Published in: World neurosurgery Vol. 149; pp. e437 - e446
• Main Authors: Niu, Shuai, Zhao, Yue, Ma, Baitao, Zhang, Rui, Rong, Zhihua, Ni, Leng, Di, Xiao, Liu, Changwei
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2021
• Subjects: Biomarkers; Hub genes; Intracranial aneurysm; Rupture; WGCNA; CC; TNFAIP6; NCF2; Rupture; DEG; ROC; GO; OSM; PPI; GSEA; IRAK3; RIA; UIA; WGCNA; BP; GEO; Hub genes; Intracranial aneurysm; LASSO; Biomarkers; IA; KEGG; TLR

Despite progress in the detection of biological molecules that contribute to intracranial aneurysm (IA) development, many pathophysiological mechanisms remain unclear, particularly with regard to predicting IA rupture. In this study, we aimed to identify hub genes and construct a new model to predic...