Effect of antioxidant diets on mitochondrial gene expression in rat brain during aging
Age-related increase of reactive oxygen species (ROS) is particularly detrimental in postmitotic tissues. Calorie restriction (CR) has been shown to exert beneficial effects, consistent with reduced ROS generation by mitochondria. Many antioxidant compounds also mimic such effects. N-acetyl cysteine...
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| Published in | Neurochemical research Vol. 30; no. 6-7; pp. 737 - 752 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Springer Nature B.V
01.06.2005
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| Abstract | Age-related increase of reactive oxygen species (ROS) is particularly detrimental in postmitotic tissues. Calorie restriction (CR) has been shown to exert beneficial effects, consistent with reduced ROS generation by mitochondria. Many antioxidant compounds also mimic such effects. N-acetyl cysteine (NAC) provides thiol groups to glutathione and to mitochondrial respiratory chain proteins; thus, it may counteract both ROS generation and effects. In the present study we investigated, in different rat brain areas during aging (6, 12, and 28 months), the effect of 1-year treatment with CR and dietary supplementation with NAC on the expression of subunit 39 kDa and ND-1 (mitochondrial respiratory complex I), subunit IV (complex IV), subunit alpha of F0F1-ATP synthase (complex V) and of adenine nucleotide translocator, isoform 1 (ANT-1). The observed age-related changes of expression were prevented by the dietary treatments. The present study provides further evidence for the critical role of mitochondria in the aging process. |
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| AbstractList | Age-related increase of reactive oxygen species (ROS) is particularly detrimental in postmitotic tissues. Calorie restriction (CR) has been shown to exert beneficial effects, consistent with reduced ROS generation by mitochondria. Many antioxidant compounds also mimic such effects. N-acetyl cysteine (NAC) provides thiol groups to glutathione and to mitochondrial respiratory chain proteins; thus, it may counteract both ROS generation and effects. In the present study we investigated, in different rat brain areas during aging (6, 12, and 28 months), the effect of 1-year treatment with CR and dietary supplementation with NAC on the expression of subunit 39 kDa and ND-1 (mitochondrial respiratory complex I), subunit IV (complex IV), subunit alpha of F0F1-ATP synthase (complex V) and of adenine nucleotide translocator, isoform 1 (ANT-1). The observed age-related changes of expression were prevented by the dietary treatments. The present study provides further evidence for the critical role of mitochondria in the aging process. Age-related increase of reactive oxygen species (ROS) is particularly detrimental in postmitotic tissues. Calorie restriction (CR) has been shown to exert beneficial effects, consistent with reduced ROS generation by mitochondria. Many antioxidant compounds also mimic such effects. N-acetyl cysteine (NAC) provides thiol groups to glutathione and to mitochondrial respiratory chain proteins; thus, it may counteract both ROS generation and effects. In the present study we investigated, in different rat brain areas during aging (6, 12, and 28 months), the effect of 1-year treatment with CR and dietary supplementation with NAC on the expression of subunit 39 kDa and ND-1 (mitochondrial respiratory complex I), subunit IV (complex IV), subunit α of F0F1-ATP synthase (complex V) and of adenine nucleotide translocator, isoform 1 (ANT-1). The observed age-related changes of expression were prevented by the dietary treatments. The present study provides further evidence for the critical role of mitochondria in the aging process. Age-related increase of reactive oxygen species (ROS) is particularly detrimental in postmitotic tissues. Calorie restriction (CR) has been shown to exert beneficial effects, consistent with reduced ROS generation by mitochondria. Many antioxidant compounds also mimic such effects. N-acetyl cysteine (NAC) provides thiol groups to glutathione and to mitochondrial respiratory chain proteins; thus, it may counteract both ROS generation and effects. In the present study we investigated, in different rat brain areas during aging (6, 12, and 28 months), the effect of 1-year treatment with CR and dietary supplementation with NAC on the expression of subunit 39 kDa and ND-1 (mitochondrial respiratory complex I), subunit IV (complex IV), subunit alpha of F sub(0)F sub(1)-ATP synthase (complex V) and of adenine nucleotide translocator, isoform 1 (ANT-1). The observed age-related changes of expression were prevented by the dietary treatments. The present study provides further evidence for the critical role of mitochondria in the aging process. |
| Author | Cuppari, C Licciardello, D Purrello, V Spina Stella, A M Giuffrida Marino, V M Patti, D Nicoletti, V G |
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| Cites_doi | 10.1523/JNEUROSCI.21-09-03017.2001 10.1097/00019052-200112000-00016 10.1006/abbi.1996.0380 10.1016/S0006-8993(97)00493-9 10.1016/S0014-5793(97)00638-8 10.1016/S0531-5565(01)00131-0 10.1152/ajpendo.00367.2003 10.1023/B:NERE.0000014825.42365.16 10.1016/S0006-8993(00)02005-9 10.1016/S0197-4580(01)00226-3 10.1111/j.1749-6632.2002.tb02094.x 10.1016/S0300-9084(00)88882-3 10.1111/j.1432-1033.1991.tb16099.x 10.1054/mehy.2000.1194 10.1023/A:1026084420943 10.1016/S0169-328X(02)00162-6 10.1046/j.0022-3042.2002.00744.x 10.1016/0003-2697(87)90021-2 10.1016/S0531-5565(99)00005-4 10.1046/j.1471-4159.2003.01586.x 10.1016/S0005-2728(98)00120-0 10.1016/S0168-9525(97)01266-3 10.1016/S0378-1119(01)00809-5 10.1038/scientificamerican0196-46 10.1023/A:1022473219044 10.1007/BF00970595 10.1038/227680a0 10.1042/bst0311295 10.1016/S0070-2137(97)80005-2 10.1093/geronj/11.3.298 10.1111/j.1471-4159.1993.tb13430.x 10.1111/j.1471-4159.1990.tb02325.x 10.1016/S0024-3205(98)00472-X 10.1016/j.exger.2003.12.003 10.1016/S0021-9258(19)52451-6 10.1002/jnr.490320313 10.1016/S0306-4522(98)00263-2 10.1146/annurev.bi.59.070190.003033 10.1046/j.1471-4159.1994.63062179.x 10.1023/B:JOBB.0000041772.74810.92 10.1016/0167-4781(94)00209-L 10.1023/A:1010730919074 10.1046/j.1474-9728.2003.00074.x 10.1023/B:NERE.0000014829.42364.dd 10.1016/S0006-8993(99)01819-3 10.1016/S0165-0270(99)00048-5 10.1159/000046889 10.1093/gerona/57.6.B211 10.1038/77046 10.1016/j.exger.2003.10.013 10.1002/(SICI)1097-4547(19980401)52:1<1::AID-JNR1>3.0.CO;2-I 10.1023/A:1010791204961 10.1016/S0968-0004(00)01688-1 10.1016/S0197-4580(97)00102-4 10.1021/bi00306a020 10.1523/JNEUROSCI.13-05-01805.1993 10.1073/pnas.051627098 10.1016/S0959-4388(96)80100-0 |
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| References | 14965349 - Aging Cell. 2004 Feb;3(1):7-12 9262186 - Brain Res. 1997 Jul 11;762(1-2):256-8 9556024 - J Neurosci Res. 1998 Apr 1;52(1):1-6 12652186 - Biogerontology. 2003;4(1):19-29 15036389 - Exp Gerontol. 2004 Mar;39(3):297-304 669401 - Growth. 1978 Mar;42(1):71-85 10491945 - J Neurosci Methods. 1999 Jul 15;89(2):141-9 11525868 - Exp Gerontol. 2001 Sep;36(9):1425-57 14907713 - J Biol Chem. 1951 Nov;193(1):265-75 11339849 - Med Hypotheses. 2001 Apr;56(4):472-7 11723388 - Curr Opin Neurol. 2001 Dec;14(6):777-81 11695835 - J Bioenerg Biomembr. 2001 Jun;33(3):251-7 11997134 - Biochim Biophys Acta. 2002 Feb 15;1553(3):249-60 8473911 - J Neurochem. 1993 May;60(5):1964-7 15038602 - Neurochem Res. 2004 Mar;29(3):547-60 9385842 - Trends Genet. 1997 Nov;13(11):450-5 8789609 - Neurochem Res. 1995 Dec;20(12):1465-70 11976197 - Ann N Y Acad Sci. 2002 Apr;959:199-213 10888876 - Nat Genet. 2000 Jul;25(3):294-7 12007832 - Brain Res Mol Brain Res. 2002 May 30;101(1-2):59-61 5432063 - Nature. 1970 Aug 15;227(5259):680-5 11312286 - J Neurosci. 2001 May 1;21(9):3017-23 2154550 - J Neurochem. 1990 Mar;54(3):823-7 2165384 - Annu Rev Biochem. 1990;59:569-96 11943463 - Gene. 2002 Mar 6;286(1):81-9 15377876 - J Bioenerg Biomembr. 2004 Aug;36(4):381-6 10363827 - Neuroscience. 1999;88(3):917-25 14736705 - Am J Physiol Endocrinol Metab. 2004 May;286(5):E852-61 7964738 - J Neurochem. 1994 Dec;63(6):2179-84 15036412 - Exp Gerontol. 2004 Feb;39(2):195-202 11351130 - Biol Signals Recept. 2001 May-Aug;10(3-4):224-53 11084368 - Trends Biochem Sci. 2000 Nov;25(11):555-60 1279190 - J Neurosci Res. 1992 Jul;32(3):415-23 10076026 - Biochim Biophys Acta. 1999 Feb 9;1410(2):183-93 10720628 - Brain Res. 2000 Mar 17;859(1):173-5 11314862 - Ann Clin Lab Sci. 2001 Jan;31(1):25-67 11695830 - J Bioenerg Biomembr. 2001 Jun;33(3):205-12 9192178 - Curr Top Cell Regul. 1997;35:123-48 9309317 - Alcohol Clin Exp Res. 1997 Sep;21(6):1053-6 11948241 - J Neurochem. 2002 Mar;80(5):780-7 8533065 - Sci Am. 1996 Jan;274(1):46-52 8806770 - Arch Biochem Biophys. 1996 Sep 1;333(1):189-97 1712295 - Eur J Biochem. 1991 Jul 1;199(1):123-31 14641046 - Biochem Soc Trans. 2003 Dec;31(Pt 6):1295-9 11226230 - Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2278-83 12558961 - J Neurochem. 2003 Feb;84(3):417-31 8386752 - J Neurosci. 1993 May;13(5):1805-19 7873605 - Biochim Biophys Acta. 1995 Feb 21;1260(3):308-14 13332224 - J Gerontol. 1956 Jul;11(3):298-300 9714734 - Biochim Biophys Acta. 1998 Aug 10;1366(1-2):53-67 8937831 - Curr Opin Neurobiol. 1996 Oct;6(5):661-6 2440339 - Anal Biochem. 1987 Apr;162(1):156-9 9390779 - Neurobiol Aging. 1997 Sep-Oct;18(5):523-6 14619982 - Mol Cell Biochem. 2003 Nov;253(1-2):313-8 11445263 - Neurobiol Aging. 2001 Jul-Aug;22(4):629-34 10227580 - Life Sci. 1999;64(15):1253-7 6477876 - Biochemistry. 1984 May 22;23(11):2449-55 15038606 - Neurochem Res. 2004 Mar;29(3):589-600 9893946 - Biochimie. 1998 Oct;80(10):871-81 9237684 - FEBS Lett. 1997 Jun 30;410(2-3):467-9 12023257 - J Gerontol A Biol Sci Med Sci. 2002 Jun;57(6):B211-24 15282183 - Biochim Biophys Acta. 2004 Jul 23;1658(1-2):122-32 10526120 - Brain Res. 1999 Sep 18;842(1):249-51 10433385 - Exp Gerontol. 1999 Jun;34(3):293-303 V. G. Nicoletti (6867_CR13) 1995; 20 K. Chandrasekaran (6867_CR45) 1992; 32 E. M. Mutisya (6867_CR18) 1994; 63 A. C. Bowling (6867_CR9) 1993; 60 A. Dubey (6867_CR63) 1996; 333 W. Chen (6867_CR47) 1997; 21 V. G. Nicoletti (6867_CR14) 1998; 80 P. Chomczynski (6867_CR32) 1987; 162 F. Cimino (6867_CR21) 1997; 35 R. A. Capaldi (6867_CR25) 1990; 59 S. K. Sandhu (6867_CR39) 2003; 4 L. Bevilacqua (6867_CR23) 2004; 286 M. P. Mattson (6867_CR66) 2003; 84 E. Fosslien (6867_CR54) 2001; 31 O. M. Lowry (6867_CR30) 1951; 193 M. McKenzie (6867_CR34) 2004; 29 E. M. Hol (6867_CR12) 1999; 88 M. M. Banaclocha (6867_CR26) 1997; 762 D. Harman (6867_CR1) 1956; 11 S. Papa (6867_CR17) 2003; 29 G. Hager (6867_CR33) 1999; 89 A. Chomin (6867_CR48) 2001; 33 R. N. Lightowlers (6867_CR15) 1997; 13 C. H. Barrows Jr. (6867_CR57) 1978; 42 M. L. Genova (6867_CR35) 1997; 410 U. K. Laemli (6867_CR31) 1970; 227 U. Schulte (6867_CR41) 2001; 33 B. T. Ashok (6867_CR2) 1999; 34 B. Ventura (6867_CR38) 2002; 1553 E. H. Sharman (6867_CR53) 2001; 22 M. Martinez (6867_CR27) 1999; 64 A. H. Schapira (6867_CR16) 1990; 54 E. Dufour (6867_CR4) 2004; 1658 R. L. Walford (6867_CR60) 2002; 57 C. K. Lee (6867_CR64) 2000; 25 M. Martinez Banaclocha (6867_CR36) 2000; 859 M. B. Graeber (6867_CR51) 1998; 52 G. Lenaz (6867_CR10) 1998; 1936 H. J. Hevner (6867_CR43) 1993; 13 F. Esposito (6867_CR20) 1995; 1260 E. A. Schon (6867_CR52) 2000; 25 R. A. Smith (6867_CR11) 2003; 31 S. Gencic (6867_CR40) 1991; 199 M. J. Coenen (6867_CR50) 2001; 14 M. Ebadi (6867_CR55) 2001; 10 S. Rao (6867_CR61) 1996; 71 G. Lenaz (6867_CR42) 2002; 959 D. E. Major (6867_CR62) 1997; 18 M. F. Beal (6867_CR7) 1996; 6 R. Cabo De (6867_CR65) 2004; 39 D. A. Di Monte (6867_CR46) 1993; 2 G. A. Cortopassi (6867_CR3) 1999; 1410 B. J. Merry (6867_CR22) 2004; 3 T. Yagi (6867_CR24) 1984; 23 K. Tanaka (6867_CR29) 2004; 39 J. E. Kokosza (6867_CR5) 2001; 98 Y. Nakagawa (6867_CR44) 2002; 101 M. M. Banaclocha (6867_CR56) 2001; 56 R. Weindruch (6867_CR58) 1996; 274 M. Martinez Banaclocha (6867_CR28) 1999; 842 M. F. Beal (6867_CR8) 2004; 36 K. S. Rao (6867_CR59) 2003; 253 G. Spiteller (6867_CR6) 2001; 36 K. Hirai (6867_CR19) 2001; 21 Y. Liu (6867_CR37) 2002; 80 R. Scarpulla (6867_CR49) 2001; 286 |
| References_xml | – volume: 21 start-page: 3017 year: 2001 ident: 6867_CR19 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.21-09-03017.2001 contributor: fullname: K. Hirai – volume: 14 start-page: 777 year: 2001 ident: 6867_CR50 publication-title: Curr. Opin. Neurol. doi: 10.1097/00019052-200112000-00016 contributor: fullname: M. J. Coenen – volume: 31 start-page: 25 year: 2001 ident: 6867_CR54 publication-title: Ann. Clin. Lab. Sci. contributor: fullname: E. Fosslien – volume: 333 start-page: 189 year: 1996 ident: 6867_CR63 publication-title: Arch. Biochem. Biophys. doi: 10.1006/abbi.1996.0380 contributor: fullname: A. Dubey – volume: 1658 start-page: 122 year: 2004 ident: 6867_CR4 publication-title: Biochem. Biophys. Acta contributor: fullname: E. Dufour – volume: 762 start-page: 256 year: 1997 ident: 6867_CR26 publication-title: Brain Res. doi: 10.1016/S0006-8993(97)00493-9 contributor: fullname: M. M. Banaclocha – volume: 410 start-page: 467 year: 1997 ident: 6867_CR35 publication-title: FEBS Lett. doi: 10.1016/S0014-5793(97)00638-8 contributor: fullname: M. L. Genova – volume: 36 start-page: 1425 year: 2001 ident: 6867_CR6 publication-title: Exp. Gerontol. doi: 10.1016/S0531-5565(01)00131-0 contributor: fullname: G. Spiteller – volume: 286 start-page: E852 year: 2004 ident: 6867_CR23 publication-title: Am. J. Physiol. Endocrinol. Metab. doi: 10.1152/ajpendo.00367.2003 contributor: fullname: L. Bevilacqua – volume: 29 start-page: 547 year: 2003 ident: 6867_CR17 publication-title: Neurochem. Res. doi: 10.1023/B:NERE.0000014825.42365.16 contributor: fullname: S. Papa – volume: 1410 start-page: 183 year: 1999 ident: 6867_CR3 publication-title: Biochem. Biophys. Acta contributor: fullname: G. A. Cortopassi – volume: 859 start-page: 173 year: 2000 ident: 6867_CR36 publication-title: Brain Res. doi: 10.1016/S0006-8993(00)02005-9 contributor: fullname: M. Martinez Banaclocha – volume: 22 start-page: 629 year: 2001 ident: 6867_CR53 publication-title: Neurobiol. Aging doi: 10.1016/S0197-4580(01)00226-3 contributor: fullname: E. H. Sharman – volume: 959 start-page: 199 year: 2002 ident: 6867_CR42 publication-title: Ann. N.Y. Acad. Sci. doi: 10.1111/j.1749-6632.2002.tb02094.x contributor: fullname: G. Lenaz – volume: 80 start-page: 871 year: 1998 ident: 6867_CR14 publication-title: Biochimie doi: 10.1016/S0300-9084(00)88882-3 contributor: fullname: V. G. Nicoletti – volume: 199 start-page: 123 year: 1991 ident: 6867_CR40 publication-title: Eur. J. Biochem. doi: 10.1111/j.1432-1033.1991.tb16099.x contributor: fullname: S. Gencic – volume: 56 start-page: 472 year: 2001 ident: 6867_CR56 publication-title: Med. Hypotheses doi: 10.1054/mehy.2000.1194 contributor: fullname: M. M. Banaclocha – volume: 253 start-page: 313 year: 2003 ident: 6867_CR59 publication-title: Mol. Cell. Biochem. doi: 10.1023/A:1026084420943 contributor: fullname: K. S. Rao – volume: 101 start-page: 59 year: 2002 ident: 6867_CR44 publication-title: Mol. Brain Res. doi: 10.1016/S0169-328X(02)00162-6 contributor: fullname: Y. Nakagawa – volume: 21 start-page: 1053 year: 1997 ident: 6867_CR47 publication-title: Alcohol Clin. Exp. Res. contributor: fullname: W. Chen – volume: 80 start-page: 780 year: 2002 ident: 6867_CR37 publication-title: J. Neurochem. doi: 10.1046/j.0022-3042.2002.00744.x contributor: fullname: Y. Liu – volume: 162 start-page: 156 year: 1987 ident: 6867_CR32 publication-title: Anal. Biochem. doi: 10.1016/0003-2697(87)90021-2 contributor: fullname: P. Chomczynski – volume: 34 start-page: 293 year: 1999 ident: 6867_CR2 publication-title: Exp. Gerontol. doi: 10.1016/S0531-5565(99)00005-4 contributor: fullname: B. T. Ashok – volume: 84 start-page: 417 year: 2003 ident: 6867_CR66 publication-title: J. Neurochem. doi: 10.1046/j.1471-4159.2003.01586.x contributor: fullname: M. P. Mattson – volume: 1936 start-page: 53 year: 1998 ident: 6867_CR10 publication-title: Biochem. Biophys. Acta doi: 10.1016/S0005-2728(98)00120-0 contributor: fullname: G. Lenaz – volume: 13 start-page: 450 year: 1997 ident: 6867_CR15 publication-title: Trends Genet. doi: 10.1016/S0168-9525(97)01266-3 contributor: fullname: R. N. Lightowlers – volume: 286 start-page: 81 year: 2001 ident: 6867_CR49 publication-title: Gene doi: 10.1016/S0378-1119(01)00809-5 contributor: fullname: R. Scarpulla – volume: 274 start-page: 46 year: 1996 ident: 6867_CR58 publication-title: Sci. Am. doi: 10.1038/scientificamerican0196-46 contributor: fullname: R. Weindruch – volume: 4 start-page: 19 year: 2003 ident: 6867_CR39 publication-title: Biogerontol. doi: 10.1023/A:1022473219044 contributor: fullname: S. K. Sandhu – volume: 20 start-page: 1465 year: 1995 ident: 6867_CR13 publication-title: Neurochem. Res. doi: 10.1007/BF00970595 contributor: fullname: V. G. Nicoletti – volume: 227 start-page: 680 year: 1970 ident: 6867_CR31 publication-title: Nature doi: 10.1038/227680a0 contributor: fullname: U. K. Laemli – volume: 31 start-page: 1295 year: 2003 ident: 6867_CR11 publication-title: Biochem. Soc. Trans. doi: 10.1042/bst0311295 contributor: fullname: R. A. Smith – volume: 35 start-page: 123 year: 1997 ident: 6867_CR21 publication-title: Curr. Top. Cell. Regul. doi: 10.1016/S0070-2137(97)80005-2 contributor: fullname: F. Cimino – volume: 11 start-page: 238 year: 1956 ident: 6867_CR1 publication-title: J. Gerontol. doi: 10.1093/geronj/11.3.298 contributor: fullname: D. Harman – volume: 60 start-page: 1964 year: 1993 ident: 6867_CR9 publication-title: J. Neurochem. doi: 10.1111/j.1471-4159.1993.tb13430.x contributor: fullname: A. C. Bowling – volume: 54 start-page: 823 year: 1990 ident: 6867_CR16 publication-title: J. Neurochem. doi: 10.1111/j.1471-4159.1990.tb02325.x contributor: fullname: A. H. Schapira – volume: 64 start-page: 1253 year: 1999 ident: 6867_CR27 publication-title: Life Sci. doi: 10.1016/S0024-3205(98)00472-X contributor: fullname: M. Martinez – volume: 39 start-page: 297 year: 2004 ident: 6867_CR65 publication-title: Exp. Gerontol. doi: 10.1016/j.exger.2003.12.003 contributor: fullname: R. Cabo De – volume: 193 start-page: 265 year: 1951 ident: 6867_CR30 publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(19)52451-6 contributor: fullname: O. M. Lowry – volume: 32 start-page: 415 year: 1992 ident: 6867_CR45 publication-title: J. Neurosci. Res. doi: 10.1002/jnr.490320313 contributor: fullname: K. Chandrasekaran – volume: 88 start-page: 917 year: 1999 ident: 6867_CR12 publication-title: Neuroscience doi: 10.1016/S0306-4522(98)00263-2 contributor: fullname: E. M. Hol – volume: 59 start-page: 569 year: 1990 ident: 6867_CR25 publication-title: Rev. Biochem. doi: 10.1146/annurev.bi.59.070190.003033 contributor: fullname: R. A. Capaldi – volume: 63 start-page: 2179 year: 1994 ident: 6867_CR18 publication-title: J. Neurochem. doi: 10.1046/j.1471-4159.1994.63062179.x contributor: fullname: E. M. Mutisya – volume: 36 start-page: 381 year: 2004 ident: 6867_CR8 publication-title: J. Bioenerg. Biomemb. doi: 10.1023/B:JOBB.0000041772.74810.92 contributor: fullname: M. F. Beal – volume: 1260 start-page: 308 year: 1995 ident: 6867_CR20 publication-title: Biochem. Biophys. Acta doi: 10.1016/0167-4781(94)00209-L contributor: fullname: F. Esposito – volume: 33 start-page: 205 year: 2001 ident: 6867_CR41 publication-title: J. Bioenerg. Biomemb. doi: 10.1023/A:1010730919074 contributor: fullname: U. Schulte – volume: 3 start-page: 7 year: 2004 ident: 6867_CR22 publication-title: Aging Cell doi: 10.1046/j.1474-9728.2003.00074.x contributor: fullname: B. J. Merry – volume: 29 start-page: 589 year: 2004 ident: 6867_CR34 publication-title: Neurochem. Res. doi: 10.1023/B:NERE.0000014829.42364.dd contributor: fullname: M. McKenzie – volume: 842 start-page: 249 year: 1999 ident: 6867_CR28 publication-title: Brain Res. doi: 10.1016/S0006-8993(99)01819-3 contributor: fullname: M. Martinez Banaclocha – volume: 1553 start-page: 249 year: 2002 ident: 6867_CR38 publication-title: Biochem. Biophys. Acta contributor: fullname: B. Ventura – volume: 89 start-page: 141 year: 1999 ident: 6867_CR33 publication-title: J. Neurosci. Methods doi: 10.1016/S0165-0270(99)00048-5 contributor: fullname: G. Hager – volume: 10 start-page: 224 year: 2001 ident: 6867_CR55 publication-title: Biol. Signals Recept. doi: 10.1159/000046889 contributor: fullname: M. Ebadi – volume: 57 start-page: B211 year: 2002 ident: 6867_CR60 publication-title: J. Gerontol. A. Biol. Sci. Med. Sci. doi: 10.1093/gerona/57.6.B211 contributor: fullname: R. L. Walford – volume: 2 start-page: 93 year: 1993 ident: 6867_CR46 publication-title: Neurodegeneration contributor: fullname: D. A. Di Monte – volume: 25 start-page: 294 year: 2000 ident: 6867_CR64 publication-title: Nat. Genet. doi: 10.1038/77046 contributor: fullname: C. K. Lee – volume: 39 start-page: 195 year: 2004 ident: 6867_CR29 publication-title: Exp. Geront. doi: 10.1016/j.exger.2003.10.013 contributor: fullname: K. Tanaka – volume: 71 start-page: 464 year: 1996 ident: 6867_CR61 publication-title: Curr. Sci. contributor: fullname: S. Rao – volume: 52 start-page: 1 year: 1998 ident: 6867_CR51 publication-title: J. Neurosci. Res. doi: 10.1002/(SICI)1097-4547(19980401)52:1<1::AID-JNR1>3.0.CO;2-I contributor: fullname: M. B. Graeber – volume: 33 start-page: 251 year: 2001 ident: 6867_CR48 publication-title: J. Bioenerg. Biomembr. doi: 10.1023/A:1010791204961 contributor: fullname: A. Chomin – volume: 25 start-page: 555 year: 2000 ident: 6867_CR52 publication-title: Trends Biochem. Sci. doi: 10.1016/S0968-0004(00)01688-1 contributor: fullname: E. A. Schon – volume: 18 start-page: 523 year: 1997 ident: 6867_CR62 publication-title: Neurobiol. Aging doi: 10.1016/S0197-4580(97)00102-4 contributor: fullname: D. E. Major – volume: 23 start-page: 2449 year: 1984 ident: 6867_CR24 publication-title: Biochemistry doi: 10.1021/bi00306a020 contributor: fullname: T. Yagi – volume: 13 start-page: 1805 year: 1993 ident: 6867_CR43 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.13-05-01805.1993 contributor: fullname: H. J. Hevner – volume: 42 start-page: 71 year: 1978 ident: 6867_CR57 publication-title: Growth contributor: fullname: C. H. Barrows Jr. – volume: 98 start-page: 2278 year: 2001 ident: 6867_CR5 publication-title: Proc. Natl. Acad. Sci. U.S.A. doi: 10.1073/pnas.051627098 contributor: fullname: J. E. Kokosza – volume: 6 start-page: 661 year: 1996 ident: 6867_CR7 publication-title: Curr. Opin. Neurobiol. doi: 10.1016/S0959-4388(96)80100-0 contributor: fullname: M. F. Beal |
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| SubjectTerms | Acetylcysteine - pharmacology Aging - metabolism Animals Antioxidants - pharmacology Base Sequence Blotting, Western Brain - drug effects Brain - metabolism Diet DNA Primers Electrophoresis, Polyacrylamide Gel Energy Intake Gene Expression Male Mitochondria - drug effects Mitochondria - genetics Rats Rats, Inbred WKY Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics |
| Title | Effect of antioxidant diets on mitochondrial gene expression in rat brain during aging |
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