Toxicological Investigation of a Case Series Involving the Synthetic Cathinone α-Pyrrolidinohexiophenone (α-PHP) and Identification of Phase I and II Metabolites in Human Urine

• Published in: Journal of analytical toxicology Vol. 47; no. 2; pp. 162 - 174
• Main Authors: Grapp, Marcel, Kaufmann, Christoph, Schwelm, Hannes M, Neukamm, Merja A
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 21.03.2023
• Subjects: Adult; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Male; Middle Aged; Pyrrolidines; Substance Abuse Detection - methods; Synthetic Cathinone; Young Adult

Abstract α-Pyrrolidinohexiophenone (α-PHP) is a derivative of the class of α-pyrrolidinophenones, a subgroup of synthetic cathinones. These substances are the second most abused drugs of new psychoactive substances. Here, we report the toxicological investigation of a series of 29 authentic forensic...