T-cadherin gene variants are associated with nephropathy in subjects with type 1 diabetes

• Published in: Nephrology, dialysis, transplantation Vol. 32; no. 12; pp. 1987 - 1993
• Main Authors: Nicolas, Anthony, Mohammedi, Kamel, Bastard, Jean-Philippe, Fellahi, Soraya, Bellili-Muñoz, Naima, Roussel, Ronan, Hadjadj, Samy, Marre, Michel, Velho, Gilberto, Fumeron, Frédéric
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.12.2017
• Subjects: Adiponectin; Adiponectin - blood; Alleles; Belgium; Belgium - epidemiology; Cadherins; Cadherins - genetics; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 1 - complications; Diabetes Mellitus, Type 1 - genetics; Diabetic Nephropathies; Diabetic Nephropathies - blood; Diabetic Nephropathies - diagnosis; Diabetic Nephropathies - epidemiology; Diabetic Nephropathies - etiology; France; France - epidemiology; Humans; Incidence; Life Sciences; Polymorphism, Genetic; Prospective Studies; Risk Factors; adiponectin; T-cadherin; type 1 diabetes; genetic polymorphisms; diabetic nephropathy; Serum amyloid A; Familial Mediterranean fever; C reactive protein

High plasma adiponectin levels are associated with diabetic nephropathy (DN). T-cadherin gene (CDH13) variants have been shown to be associated with adiponectin levels. We investigated associations between allelic variations of CDH13 and DN in subjects with type 1 diabetes. Two CDH13 polymorphisms w...