Effects of structural modifications on the photosensitizing properties of dialkylcarbocyanine dyes in homogeneous and heterogeneous solutions

• Published in: Biochimica et biophysica acta Vol. 1199; no. 2; pp. 149 - 156
• Main Authors: Krieg, Marianne, Bilitz, James M., Srichai, Monvadi B., Redmond, Robert W.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 02.03.1994
• Subjects: Carbocyanines - chemistry; Carbocyanines - pharmacology; Cyanine dyes; Heavy atom effect; Liposomes; Liposomes - metabolism; Molecular Structure; Oxygen - metabolism; Photochemistry; Photophysics; Photosensitization; Photosensitizing Agents - chemistry; Photosensitizing Agents - pharmacology; Selenium - chemistry; Singlet oxygen; Solutions; Spectrometry, Fluorescence; Structure-Activity Relationship; Sulfur - chemistry; Temperature; Cyanine dyes; φ f; φ isc; MC540; 1O 2; ϵ T; Photophysics; DPBF; Singlet oxygen; φ Δ; Photosensitization; Heavy atom effect; Liposomes; DMPC

The photophysical characterization of structurally modified symmetric dialkylthiacarbocyanine dyes in homogenous and biomimetic media is reported. The aim of the two specific structural modifications was to increase singlet oxygen production, hence enhancing the photosensitizing properties of these...